Calcium Regulation of Membrane Biogenesis in Fusogenic Carrot Protoplasts

融合胡萝卜原生质体膜生物发生的钙调节

• 批准号: 8812580
• 负责人: Wendy Boss
• 金额: $ 45.66万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-01 至 1994-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8812580&HistoricalAwards=false
• 关键词: Calcium; Regulation; Membrane; Biogenesis; Fusogenic

This is is a proposal on phosphoinositide research that is currently an area of great interest in relation to second messenger models both in animal and plant cells. The Principal Investigator has already demonstrated the importance of phospholipase and phosphoinositide in membrane fusion. The current project will focus on membrane lysophatidylinositol 4- triphosphate (LPIP), its synthetic pathways and catabolism, its functional significance and regulatory mechanism. Biochemical, immunochemical and molecular techniques will be used to achieve the objectives. Since the project will help identify parameters that promote membrane fusion, it could have important ramifications in biotechnology.

这是一个关于磷酸肌醇研究的建议， 目前，这是一个非常感兴趣的领域， 动物和植物细胞中的信使模型。 校长 研究人员已经证明了 磷脂酶和磷酸肌醇。的 目前的项目将集中在膜lysophatidylinositol 4- 三磷酸（LPIP），其合成途径和催化剂，其 功能意义和调控机制。生物化学， 免疫化学和分子技术将用于实现 目标。 由于该项目将有助于确定参数 促进细胞膜融合， 生物技术的分支。