Single-Molecule Studies of Surfactant Mobility at the Solid/Solution Interface

固体/溶液界面表面活性剂迁移率的单分子研究

• 批准号: 0841116
• 负责人: Daniel Schwartz
• 金额: $ 50.2万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0841116&HistoricalAwards=false
• 关键词: Single; Molecule; Studies; Surfactant; Mobility

The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry supports the research program of Professor Daniel K. Schwartz of the University of Colorado at Boulder. Prof. Schwartz and his coworkers are developing and employing total internal fluorescence microscopy methods to study the dynamic behavior of individual molecules as they adsorb and move at the solid/liquid interface. They are also developing new methods that can probe molecular proximity and conformation simultaneously as this behavior is studied. This project will lead to a fundamentally new understanding of the way molecules interact with and move on surfaces; this information will impact a number of technological areas, including microarrays for medical diagnostics, catalytic conversion of biomass to biofuels, pharmaceutical separations, and others. Moreover, it will enable advances in nanotechnology -in particular the use of molecular self-assembly to prepare miniaturized structures and devices. The graduate students and postdoctoral researchers who work on this project are trained to become innovative researchers or leaders in the high-tech industry. Through this project, Prof. Schwartz and his coworkers are also providing research training for undergraduate students as well as enrichment opportunities for K-12 students through programs including the Colorado High School Honors Institute and the Science at CU outreach program.

化学部的分析和表面化学（ASC）计划支持丹尼尔K教授的研究计划。位于博尔德的科罗拉多大学的施瓦茨说。Schwartz教授和他的同事正在开发和采用全内荧光显微镜方法来研究单个分子在固/液界面吸附和移动时的动态行为。 他们还在开发新的方法，可以同时探测分子的接近性和构象，因为这种行为正在研究中。 该项目将导致对分子与表面相互作用和在表面上移动的方式的全新理解;这些信息将影响许多技术领域，包括用于医学诊断的微阵列，生物质催化转化为生物燃料，药物分离等。 此外，它将促进纳米技术的发展，特别是利用分子自组装来制备微型结构和装置。 从事该项目的研究生和博士后研究人员将被培养成为高科技行业的创新研究人员或领导者。 通过这个项目，教授施瓦茨和他的同事还提供了本科生的研究培训，以及丰富的机会，为K-12学生通过计划，包括科罗拉多高中荣誉研究所和科学在CU外展计划。