Single-Molecule Studies of Surfactant Mobility at the Solid/Solution Interface

化学系的分析和表面化学（ASC）项目支持科罗拉多大学博尔德分校的Daniel K. Schwartz教授的研究项目。施瓦茨教授和他的同事正在开发和使用全内部荧光显微镜方法来研究单个分子在固/液界面吸附和移动时的动态行为。他们还在开发新的方法，可以在研究这种行为的同时探测分子的接近性和构象。这个项目将导致对分子相互作用和在表面上移动的方式的全新理解；这些信息将影响许多技术领域，包括用于医学诊断的微阵列、生物质催化转化为生物燃料、药物分离等。此外，它将推动纳米技术的进步，特别是利用分子自组装来制备小型化结构和设备。从事该项目的研究生和博士后研究人员将被培养成为创新型研究人员或高科技行业的领导者。通过这个项目，施瓦茨教授和他的同事们还为本科生提供研究培训，并通过包括科罗拉多高中荣誉学院和科罗拉多大学科学外展计划在内的项目为K-12学生提供丰富的机会。

The Analytical and Surface Chemistry (ASC) program of the Division of Chemistry supports the research program of Professor Daniel K. Schwartz of the University of Colorado at Boulder. Prof. Schwartz and his coworkers are developing and employing total internal fluorescence microscopy methods to study the dynamic behavior of individual molecules as they adsorb and move at the solid/liquid interface. They are also developing new methods that can probe molecular proximity and conformation simultaneously as this behavior is studied. This project will lead to a fundamentally new understanding of the way molecules interact with and move on surfaces; this information will impact a number of technological areas, including microarrays for medical diagnostics, catalytic conversion of biomass to biofuels, pharmaceutical separations, and others. Moreover, it will enable advances in nanotechnology -in particular the use of molecular self-assembly to prepare miniaturized structures and devices. The graduate students and postdoctoral researchers who work on this project are trained to become innovative researchers or leaders in the high-tech industry. Through this project, Prof. Schwartz and his coworkers are also providing research training for undergraduate students as well as enrichment opportunities for K-12 students through programs including the Colorado High School Honors Institute and the Science at CU outreach program.