Workshop On: Micro/Nanoelectronics: Devices and Technologies for Biomedical Applications. The Workshop will be held at IMEC in Leuven, Belgium from September 25-26, 2008.

研讨会主题：微/纳米电子学：生物医学应用设备和技术。

• 批准号: 0843482
• 负责人: Kensall Wise
• 金额: $ 4.91万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-15 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0843482&HistoricalAwards=false
• 关键词: Workshop; Micro; Nanoelectronics; Devices; Technologies

AbstractObjective This objective of this proposal is to request funding to support a workshop aimed at speeding the development of micro/nanoelectronic devices for improved healthcare. The workshop will be held at the Interdisciplinary Microelectronics Center (IMEC) in Leuven, Belgium on September 25-26, 2008. The workshop will bring together leading researchers from the microsystem and nanobiotechnology communities to identify grand challenges, promote collaborations, and recommend research needed to speed the use of these technologies in biology and biomedicine. This workshop will bring together scientists and engineers from micr/nano communities and biology and biomedicine and will try to identify devices and systems that could be used for in-vivo and in-vitro applications. The two disciplines seem destined to meet at cellular dimensions, and this workshop seeks to bridge the gap between them.Intellectual Merit:After nearly four decades, many of the microelectronic technologies needed for health care are now emerging. Sophisticated signal processing tasks involving millions of transistors can be performed on a single chip at microwatt levels. Wireless technology has created global communication networks and is being reduced to single chips capable of working in-vivo. MEMS-based sensors now exist for many physiological parameters, and hermetic wafer-level packaging techniques suitable for use in implants are emerging. Structures based on nanotechnology are being combined with microfluidics and being developed to analyze DNA and screen for proteomic biomarkers of Alzheimer?s disease, heart disease, and cancer. But many challenges remain. Improved power sources are needed, some perhaps based on energy scavenging, and the critical interface between the biological environment and physical monitoring devices must be much better understood. True advances in health care will likely require the integration of both. Broader impact:Health care is one of the most important problems confronting the 21st century. In 2000, life expectancies ranged from 35 years in Sierra Leone to 77 in the U.S. and 83 in Japan, and in U.S. the cost of health care represented 13% of GDP. About 630 million people worldwide were over the age of 60, but by 2050 this number will increase to over two billion, an increase of 330%. Clearly something must be done to avoid catastrophic health care cost. Diagnostic devices based on cellular/molecular analysis and implantable microsystems for treating many of our most serious chronic disorders are among the most promising approaches for meeting these challenges.

摘要目的 本提案的目标是请求资金支持一个研讨会，该研讨会旨在加速微/纳米电子设备的开发，以改善医疗保健。 该研讨会将于 2008 年 9 月 25 日至 26 日在比利时鲁汶的跨学科微电子中心 (IMEC) 举行。该研讨会将汇集来自微系统和纳米生物技术界的领先研究人员，以确定重大挑战，促进合作，并推荐加快这些技术在生物学和生物医学中的应用所需的研究。 该研讨会将汇集来自微/纳米领域以及生物学和生物医学领域的科学家和工程师，并将尝试确定可用于体内和体外应用的设备和系统。 这两个学科似乎注定会在细胞维度上相遇，本次研讨会旨在弥合它们之间的差距。 智力优势：经过近四十年的发展，医疗保健所需的许多微电子技术现已出现。涉及数百万个晶体管的复杂信号处理任务可以在微瓦级的单个芯片上执行。 无线技术已经创建了全球通信网络，并且正在被简化为能够在体内工作的单芯片。 现在存在用于许多生理参数的基于 MEMS 的传感器，并且适用于植入物的密封晶圆级封装技术正在出现。基于纳米技术的结构正在与微流体相结合，并被开发用于分析 DNA 和筛选阿尔茨海默病、心脏病和癌症的蛋白质组生物标志物。但仍然存在许多挑战。 需要改进的电源，其中一些可能基于能量收集，并且必须更好地理解生物环境和物理监测设备之间的关键接口。医疗保健的真正进步可能需要两者的结合。更广泛的影响：医疗保健是 21 世纪面临的最重要问题之一。 2000年，塞拉利昂的预期寿命为35岁，美国为77岁，日本为83岁，而美国的医疗保健费用占GDP的13%。全球约有6.3亿人年龄在60岁以上，但到2050年，这一数字将增至超过20亿，增长330%。显然，必须采取一些措施来避免灾难性的医疗费用。 基于细胞/分子分析的诊断设备和用于治疗许多最严重的慢性疾病的可植入微系统是应对这些挑战的最有希望的方法之一。