X-ray Scattering Studies of Interfaces Between Two Immiscible Electrolyte Solutions

芝加哥伊利诺伊大学的Mark L.Schlossman教授和北伊利诺伊大学的Petr Vanysek教授得到化学系分析和表面化学计划的支持，对不相容的电解质溶液之间的界面进行X射线散射研究。这项研究的目的是系统地表征离子在两种不相容的电解质溶液之间的界面上的分布，并探索吸附在液-液界面上的脂单分子层上蛋白质-脂类结合的结构依赖性。PI将结合X射线表面散射和现场电化学测量来实现这些目标。这项工作将促进我们对液/液体系界面结构的理解，并检验支持液/液界面分析和计算研究的基本假设。这项研究也有望促进我们对膜蛋白结构-功能关系的理解，膜蛋白在细胞信号传递和运输中发挥着基础作用。研究生和本科生以及博士后将接受使用X射线散射方法解决液/液界面的电化学问题的培训，并将接触到广泛的研究学科。

Professor Mark L. Schlossman of the University of Illinois at Chicago and Professor Petr Vanysek of Northern Illinois University are supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to conduct X-ray scattering studies on interfaces between immiscible electrolyte solutions. The goals of the proposed research is to systematically characterize the distribution of ions across interfaces between two immiscible electrolyte solutions, and to explore the structural dependence of protein-lipid binding at lipid monolayers adsorbed to liquid-liquid interfaces. The PIs will combine X-ray surface scattering with in situ electrochemical measurements to achieve these goals. The proposed work will advance our understanding of interfacial structure of liquid/liquid systems, and test fundamental assumptions underlying analytical and computational studies of the liquid/liquid interface. This research is also expected to advance our understanding of the structure-function relationship of membrane proteins that play a fundamental role in cell signaling and trafficking. Graduate and undergraduate students as well as post-doctoral associates will be trained in the use of X-ray scattering methods to solve electrochemical problems at the liquid/liquid interface, and will be exposed to a broad range of research disciplines.