X-ray Scattering Studies of Interfaces Between Two Immiscible Electrolyte Solutions

Mark L.教授在化学系分析和表面化学项目的支持下，位于芝加哥的伊利诺斯大学的Schlossman和北方伊利诺斯大学的Petr Vanysek教授对不混溶电解质溶液之间的界面进行了X射线散射研究。 拟议的研究的目标是系统地表征两个不混溶的电解质溶液之间的界面的离子分布，并探讨在脂质单层吸附到液-液界面的蛋白质-脂质结合的结构依赖性。 PI将联合收割机X射线表面散射与现场电化学测量相结合，以实现这些目标。 建议的工作将推进我们的理解的界面结构的液体/液体系统，并测试基本假设的分析和计算研究的液体/液体界面。 这项研究也有望促进我们对膜蛋白结构-功能关系的理解，这些膜蛋白在细胞信号传导和运输中起着重要作用。研究生和本科生以及博士后将接受使用X射线散射方法解决液/液界面电化学问题的培训，并将接触到广泛的研究学科。

Professor Mark L. Schlossman of the University of Illinois at Chicago and Professor Petr Vanysek of Northern Illinois University are supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to conduct X-ray scattering studies on interfaces between immiscible electrolyte solutions. The goals of the proposed research is to systematically characterize the distribution of ions across interfaces between two immiscible electrolyte solutions, and to explore the structural dependence of protein-lipid binding at lipid monolayers adsorbed to liquid-liquid interfaces. The PIs will combine X-ray surface scattering with in situ electrochemical measurements to achieve these goals. The proposed work will advance our understanding of interfacial structure of liquid/liquid systems, and test fundamental assumptions underlying analytical and computational studies of the liquid/liquid interface. This research is also expected to advance our understanding of the structure-function relationship of membrane proteins that play a fundamental role in cell signaling and trafficking. Graduate and undergraduate students as well as post-doctoral associates will be trained in the use of X-ray scattering methods to solve electrochemical problems at the liquid/liquid interface, and will be exposed to a broad range of research disciplines.