MRI: Acquisition of a Single Crystal X-ray Diffractometer

通过主要研究仪器（MRI）项目的奖励，来自明尼苏达大学德卢斯分校的Viktor Nemykin教授及其同事将获得一台带有CCD探测器的单晶x射线衍射仪，用于化学研究，包括：1)双核镧系配合物的表征，2)新的β -羟基酯合成当量的研究，3)刚地弓形虫抑制剂的构效研究，4)高价过渡金属芳烃配合物的研究，5)有机天然产物的结构分析等项目。除了明尼苏达大学德卢斯分校的用户可以使用外，圣斯考拉斯蒂卡学院（德卢斯，MN）和威斯康辛大学苏必利尔分校的研究人员也将使用该仪器进行自己的研究项目。单晶x射线晶体学技术允许精确和精确地测定分子的完整三维结构，包括键的距离和角度，它提供了分子相对于邻近分子的空间排列的准确信息。这些研究将在许多领域产生影响，从合成有机和无机化学到生物兴趣系统和材料研究。该仪器将成为教学和研究的一个组成部分，并将服务于目前没有现代晶体学设备的地区（明尼苏达州北部和威斯康星州北部）的大学和学院。

With this award from the Major Research Instrumentation (MRI) program, Professor Viktor Nemykin and colleagues from the University of Minnesota - Duluth will acquire a single crystal X-ray diffractometer with a CCD detector for use in chemical research, including: 1) characterization of binuclear lanthanide complexes, 2) studies with a new beta-hydroxy ester synthon equivalent, 3) structure-activity studies of toxoplasma gondii inhibitors, 4) studies of high-valent transition metal arene complexes, 5) structural analysis of organic natural products, and other projects. Besides being available to users at the University of Minnesota -- Duluth, researchers at the College of St. Scholastica (Duluth, MN) and University of Wisconsin - Superior will also use the instrument for their own research projects.The technique of single-crystal X-ray crystallography allows accurate and precise determination of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of molecules relative to the neighboring molecules. These studies will have an impact in a number of areas ranging from synthetic organic and inorganic chemistry to systems of biological interest and materials research. This instrument will be an integral part of teaching as well as research, and will serve universities and colleges in a region of the country (northern Minnesota and northern Wisconsin) that do not currently have modern crystallography facilities.