MRI: Acquisition of A Single-Crystal X-Ray Diffractometer—Synthesize, Crystallize, Virtualize

该奖项由主要研究仪器项目和化学研究仪器项目共同支持。路易斯安那州立大学正在获取一台配备铜和银X射线源的双源单晶衍射仪、一个增强型探测器和一个低温设备，以支持Semin Lee教授及其同事Noemie Elgrishi、Victor Garcia Lopez、Matthew Chambers和Fatima Rivas的研究。通常，X射线衍射仪可以准确和精确地测量分子的完整三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响到许多领域，包括有机化学和无机化学、材料化学、生物化学和催化。该仪器是该机构化学和生物化学专业本科生和研究生教学、科研和培训不可或缺的一部分。李教授和他的合作者正在开发一个项目，以加强基于虚拟现实的教学，结合路易斯安那州许多HBCU/Pui机构的合成和结晶学项目。该奖项旨在加强所有级别的研究和教育。该仪器支持的研究集中在炔烃歧化催化剂、分子金属笼、天然产物、与能量相关的转化分子催化剂、光激活分子马达、基于二吡咯亚硼的荧光团、用于药物发现的新有机反应、蛋白质结构：沙眼衣原体、量子材料。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Louisiana State University is acquiring a dual-source single crystal diffractometer equipped with Cu and Ag X-ray sources, an enhanced detector, and a cryogenic device to support the research of Professor Semin Lee and colleagues Noemie Elgrishi, Victor Garcia Lopez, Matthew Chambers, Fatima Rivas. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry, biochemistry, and catalysis. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution. Professor Lee and his collaborators are developing a program to enhance virtual reality-based teaching, combined with synthesis and crystallography projects at a number of HBCU/PUI institutions throughout Louisiana.The award is aimed at enhancing research and education at all levels. Research enabled by the instrument is focused on alkyne metathesis catalysts, molecular metallo-cages , natural products, molecular catalysts for energy- relevant transformations, light-activated molecular motors, boron dipyrromethene-based fluorophores, new organic reactions for drug discovery, protein structure: chlamydia trachomatis, quantum materials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.