MRI: Acquisition of a Dual-Source Single-Crystal X-ray Diffractometer.

该奖项由主要研究仪器和化学研究仪器项目联合支持。圣母大学正在购买一个双源单晶衍射仪，配备高通量Cu和Mo微聚焦x射线源，一个CPAD探测器和一个低温设备，以支持Allen Oliver教授及其同事Vlad Iluc和Emily Tsui的研究。一般来说，x射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响许多领域，包括有机和无机化学，材料化学和生物化学。该仪器是该机构化学和生物化学本科生和研究生的教学、研究和研究训练的一个组成部分。该设施作为区域XRD资源，通过与田纳西理工大学、圣玛丽学院、伊丽莎白镇学院和不列颠哥伦比亚省维多利亚大学等机构的研究人员的积极合作，使印第安纳州主要本科院校的学生和教师受益，并对ND以外的地区产生影响，并保持私营部门的隶属关系。他们与智利、加拿大和新西兰的同事开展了国际合作。该奖项旨在加强各级的研究和教育。该仪器的研究重点是研究和表征各种各样的物质，包括对映纯和手性有机化合物、药物前体和其他生物重要分子、有机金属和无机配合物以及矿物样材料。金属配合物（如催化）、固态材料（如能量转换）和光原子分子（如天然产物）的绝对构型的结构确定对于推动这些领域的研究至关重要。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. The University of Notre Dame is acquiring a dual-source single crystal diffractometer equipped with high-flux Cu and Mo microfocus X-ray sources, a CPAD detector, and a cryogenic device to support the research of Professor Allen Oliver and colleagues Vlad Iluc, and Emily Tsui. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution. The facility serves as a regional XRD resource benefitting students and faculty from primarily undergraduate institutions within the state of Indiana with impacts outside ND through active collaborations with researchers at institutions such as Tennessee Tech University, St. Mary’s College, Elizabethtown College, and the University of Victoria, B.C., and maintains private sector affiliations. They have developed international collaborations with colleagues from Chile, Canada, and New Zealand.The award is aimed at enhancing research and education at all levels. Research enabled by the instrument is focused on the study and characterization of a wide variety of substances including enantiopure and chiral organic compounds, drug precursors and other biologically important molecules, organometallic and inorganic complexes and mineral-like materials. Structure determination of metal complexes (e.g., catalysis), solid-state materials (e.g., energy conversion), and absolute configurations of light-atom molecules (e.g., natural products) is essential to drive research in these fields.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.