MRI: Acquisition of a Single Crystal X-ray Diffractometer for Undergraduate Research and Training

凭借这一重大研究仪器（MRI）计划的奖项，Benny Chan和同事Heba Abourahma，格鲁吉亚M。作者：大卫亨特和斯蒂芬妮E.来自新泽西学院的Sen将获得一台单晶X射线衍射仪，以支持以下研究：1）硫属化物材料的合成和表征; 2）对铜扁柏酚及其加合物的研究; 3）帕勒姆环化的不对称诱导; 4）利用仿生多烯环化方法构建多环; 5）作为活性药物成分的共晶，和6）有机杂环化学。与普林斯顿大学在固体化学和物理学方面的合作也将展开。单晶X射线晶体学技术可以准确和精确地确定分子的完整三维结构，包括键距和键角，并提供分子相对于相邻分子的空间排列的准确信息。这些研究将对从合成有机和无机化学到生物学系统等许多领域产生影响。该仪器将成为教学和研究的一个组成部分。

With this award from the Major Research Instrumentation (MRI) program, Benny Chan and colleagues Heba Abourahma, Georgia M. Arvanitis, David Hunt and Stephanie E. Sen from The College of New Jersey will acquire a single-crystal X-ray diffractometer to support research that includes: 1) synthesis and characterization of chalcogenide materials; 2) studies on copper hinokitiol and its adducts; 3) asymmetric induction into Parham cyclizations; 4) polycycle construction utilizing biomimetic polyene cyclization methods; 5) co-crystals as active pharmaceutical ingredients, and 6) organic heterocycle chemistry. Collaborations with Princeton University in solid state chemistry and physics will also take place.The technique of single-crystal X-ray crystallography allows accurate and precise determination of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of molecules relative to the neighboring molecules. These studies will have an impact in a number of areas ranging from synthetic organic and inorganic chemistry to systems of biological interest. This instrument will be an integral part of teaching as well as research.