MRI: Acquisition for High-resolution magnetic resonance imaging of the primate brain

MRI：采集灵长类大脑的高分辨率磁共振成像

• 批准号: 0922982
• 负责人: Ralph Adolphs
• 金额: $ 102.34万
• 依托单位: California Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2013-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922982&HistoricalAwards=false
• 关键词: MRI; Acquisition; resolution; magnetic; resonance

This three-year grant will purchase two pieces of equipment for magnetic resonance imaging of the brain at the California Institute of Technology. One equipment piece provides the best resolution in a horizontal orientation; the second provides imaging of behaving monkeys in vertical position. This will provide state-of-the-art tools for investigating brain structure and function in monkeys with noninvasive methods, and also provide opportunities for imaging post-mortem human brains. The technology will make possible a set of research studies on how the brain processes information, including how it sees faces, how it weighs different choices, and how it makes decisions and guides action. These are important questions in neuroscience, and the new equipment will greatly enhance science at the Caltech Brain Imaging Center. The grant will also provide opportunities for training of students and post-docs on the new equipment. This will include classes taught at Caltech as well as participation in individual research projects. The development of these new scientific tools will lead to a better understanding of how the brain works, and how it is "wired up." That knowledge, in turn, will contribute to efforts to build artificially intelligent systems. Taken together, the cutting-edge science enabled by the new equipment, and the training of the next generation of young scientists on it, will contribute substantially to cognitive neuroscience in America and worldwide.

这笔为期三年的赠款将在加州理工学院购买两台用于大脑磁共振成像的设备。 一台设备可提供水平方向的最佳分辨率；第二个提供猴子在垂直位置的行为成像。 这将为通过非侵入性方法研究猴子的大脑结构和功能提供最先进的工具，并为死后人类大脑成像提供机会。 该技术将使一系列关于大脑如何处理信息的研究成为可能，包括如何看待面孔、如何权衡不同的选择以及如何做出决策和指导行动。 这些都是神经科学中的重要问题，新设备将极大地增强加州理工学院脑成像中心的科学水平。这笔赠款还将为学生和博士后提供新设备培训的机会。 这将包括在加州理工学院教授的课程以及参与个人研究项目。 这些新科学工具的开发将有助于更好地理解大脑如何工作以及它如何“连接”。 这些知识反过来将有助于构建人工智能系统。 总而言之，新设备带来的尖端科学以及对下一代年轻科学家的培训将为美国和全世界的认知神经科学做出重大贡献。