Engineering synthetic genetic codes

工程合成遗传密码

• 批准号: FT0991113
• 负责人: Prof Oliver Rackham
• 金额: $ 48.96万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-03-01 至 2014-08-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT0991113
• 关键词: Engineering; synthetic; genetic; codes

Large, high quality libraries of new drugs are absolutely essential resources to find new medicines. However, their use is restricted to a few pharmaceutical giants. We will engineer cells to make a wide variety of drug-like polymers, providing a drug discovery resource accessible to almost any scientific laboratory. As each cell could make a different polymer, billions of different potential drugs could be produced in a single tube. This technology provides an opportunity to put the future of drug discovery in the hands of the wider scientific community and new tools for Australian industries.

大型、高质量的新药库是寻找新药的绝对必要资源。然而，它们的使用仅限于少数制药巨头。我们将工程细胞，使各种各样的药物样聚合物，提供药物发现资源访问几乎任何科学实验室。由于每个细胞可以制造不同的聚合物，因此可以在单个试管中生产数十亿种不同的潜在药物。这项技术提供了一个机会，将药物发现的未来交给更广泛的科学界和澳大利亚工业的新工具。