SBIR Phase I: Detection and Determination of Viability of Cryptospordium Oocysts by Capillary Column Immunosensor

SBIR 第一阶段：通过毛细管柱免疫传感器检测和测定隐孢子虫卵囊的活力

• 批准号: 0945184
• 负责人: Lisa Bielke
• 金额: $ 15万
• 依托单位: BioDetection Instruments, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0945184&HistoricalAwards=false
• 关键词: SBIR; Phase; Detection; Determination; Viability

This SBIR Phase I project will develop a method to detect Cryptosporidium oocysts at a level of 100 oocysts/L or lower, and to differentiate between viable and non-viable cysts. The team will use a prototype of a capillary-based immunosensor (AEGIS 1000 instrument) coupled with heat and lysis treatment to detect Cryptosporidium in water.The broader/commercial impact of the project will be the commercialization of the prototype of capillary-based immunosensor, which has the potential to extend its application in the water industry for live waterborne pathogen detection. This will allow water utilities to promptly respond to and correct a microbial contamination event.

该SBIR第一阶段项目将开发一种方法，以检测100个卵囊/L或更低水平的隐孢子虫卵囊，并区分存活和非存活包囊。 该团队将使用基于毛细管的免疫传感器原型（AEGIS 1000仪器）结合热裂解处理来检测水中的隐孢子虫。该项目的更广泛/商业影响将是基于毛细管的免疫传感器原型的商业化，这有可能扩展其在水工业中的应用，用于活体水生病原体检测。 这将使供水公司能够迅速应对和纠正微生物污染事件。