Console Replacement for a 20-Year Old 400 MHz Open Access NMR Spectrometer

更换使用 20 年的 400 MHz 开放式核磁共振波谱仪的控制台

• 批准号: 0946687
• 负责人: Jacob Petrich
• 金额: $ 19.39万
• 依托单位: Iowa State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0946687&HistoricalAwards=false
• 关键词: Console; Replacement; 20; Year; Old

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor Jacob W. Petrich and colleagues from the Department of Chemistry at Iowa State University will upgrade a 400 MHz NMR spectrometer. The upgraded instrument will enable rapid 2D measurements with pulse field gradients and reliable 1D with increased sensitivity, and will have variable temperature capabilities. The instrument will be used to support research activities such: 1) preparation of organometallic compounds that contain a range of heteroatoms including boron, phosphorus, nitrogen, fluorine, and silicon; 2) synthetic methodologies and applications in combinatorial chemistry; 3) elucidation of the roles of structurally directed electron induction and transannulation in polycyclic Lewis base and acid catalysis; 4) environmentally responsive materials, sensors and catalysis; 5) green catalysis; and 6) custom carbohydrate synthesis.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have a positive impact in synthetic organic/inorganic chemistry, materials, the environment and biochemistry. This instrument will be an integral part of teaching as well as research.

通过化学研究仪器和设施：部门多用户仪器项目（CRIF:MU）的奖励，爱荷华州立大学化学系的Jacob W. Petrich教授和他的同事将升级一台400 MHz核磁共振光谱仪。升级后的仪器将实现脉冲场梯度的快速二维测量和可靠的一维测量，灵敏度更高，并具有可变温度能力。该仪器将用于支持以下研究活动：1)制备含有一系列杂原子的有机金属化合物，包括硼、磷、氮、氟和硅；合成方法及其在组合化学中的应用；3)阐明了结构定向电子诱导和转环在多环刘易斯碱和酸催化中的作用；4)环境响应材料、传感器和催化剂；5)绿色催化；6)定制碳水化合物合成。核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对合成有机/无机化学、材料、环境和生物化学产生积极的影响。该仪器将成为教学和研究的一个组成部分。