Acquisition of an accurate mass quadrupole time of flight mass spectrometer

该奖项是根据2009年《美国复苏和再投资法案》(Public Law 111-5)获得的。在化学研究仪器和设施：多用户计划(CRIF：MU)的这一奖项下，爱荷华州立大学化学系的Jacob W.Petrich将为该部门的质谱分析实验室购买一台网络控制的精确质量液相四极杆(LCMS/MS)质谱仪。该光谱仪具有基于溶液的样品导入、四极杆/离子陷阱前体选择和飞行时间(TOF)质谱仪。该仪器将支持几种形式的大气压电离(API)和两种电离方法：电喷雾(ESI)和化学电离(APCI)。该光谱仪将支持参与基础研究的不同教职员工和科学家的努力，为复杂的化学问题开发解决方案，从生物化学到催化过程，以改进大豆油的加工，再到生产新材料，以捕捉阳光和发光二极管的能量。来自LaRock、Pohl、Kraus、Verkade、Jenks和Jeffries-El教授研究小组的学生将使用该仪器，以及来自化学、生物化学、化学工程、农学、食品科学、植物学、地质学和昆虫学等系的其他研究小组。LC MS/MS-TOF-MS是一种获得超大分子精确分子量的重要技术，具有极高的灵敏度。因此，使用LC MS/MS-TOF质谱计已成为一种标准技术，特别是在涉及生物分子的研究中。这项研究将在许多领域产生重大影响，特别是化学和生物化学。该仪器将成为教学和研究不可或缺的一部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Chemistry Research Instrumentation and Facilities: Multiuser program (CRIF:MU), Jacob W. Petrich from the Department of Chemistry at Iowa State University will acquire a cyber-enabled accurate-mass liquid chromatography, quadrupole (LCMS/MS) mass spectrometer for the Department's Mass Spectrometry Laboratory. This spectrometer possesses a solution-based sample introduction, quadrupole/ion trap precursor selection, and a time-of-flight (TOF) mass analyzer. This instrument will accommodate several forms of atmospheric pressure ionization (API) and two ionization methods: electrospray (ESI) and chemical ionization (APCI). The spectrometer will support the efforts of a diverse group of faculty and scientists involved in fundamental research to developing solutions to complex chemical problems varying from biological chemistry to catalytic processes to improve processing of soy bean oil to production of new materials to capture the energy of sunlight and light emitting diodes. Students from research groups of professors Larock, Pohl, Kraus, Verkade, Jenks and Jeffries-EL will utilize the instrument as well as other research groups from departments including chemistry, biochemistry, chemical engineering, agronomy, food science, botany, geology and entomology.LCMS/MS-TOF-mass spectrometry is an important technique for obtaining accurate molecular weights on very large molecules, with extremely high sensitivity. Use of a LCMS/MS-TOF mass spectrometer has therefore become a standard technique, especially in studies involving biomolecules. This research will have a significant impact in a number of areas, especially chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.