Engineering Metal-Organic Framework Catalysts using Postsynthetic Modification

使用合成后改性工程金属有机框架催化剂

• 批准号: 0952370
• 负责人: Seth Cohen
• 金额: $ 44万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-15 至 2013-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0952370&HistoricalAwards=false
• 关键词: Engineering; Metal; Organic; Framework; Catalysts

The Chemical Catalysis Program supports Professor Seth M. Cohen at the University of California- San Diego for a research project that will use post-synthetic modification (PSM) to alter metal organic framework (MOF) materials to introduce a range of functionalities without disrupting the overall structure and porosity of the MOFs. Post-synthetic modification is emerging as a useful tool to access functionalized MOFs that cannot be prepared directly. These materials will be useful as both homogeneous and heterogeneous catalysts. Although there are now quite a few examples of MOFs that have been used as heterogeneous catalysts, the proposal correctly identifies catalysis as an area of MOF chemistry that is under-developed. Preliminary studies show that chiral substituents, organocatalytic groups (carboxylic acids, ureas), and metal-binding groups can be readily introduced into MOFs by PSM. Early studies show that these modified MOFs are useful for catalytic reactions.With the support of the Chemical Catalysis Program in the Chemistry Division at the National Science Foundation, Dr. Cohen will perform research that contributes to metal-organic frameworks (MOFs) becoming more widespread as a material of choice for energy, catalysis, and biomedical applications. Based on these technological applications, and because of the growing importance of postsynthetic modification (PSM) of MOFs, Professor Cohen's work has garnered substantial attention from outside the immediate MOF community. Most notably is a recent paper on the use of MOFs as solid-state catalysts via PSM (Angew. Chem. 2009) that has gathered substantial attention in the catalysis discipline. This proposal also includes a novel broader impacts/teaching activity to develop internships and coursework in science policy. A Science Policy Summer Program at the University of California Center in Washington D.C. (called UC in DC) is being created. The PI is the Director of this new program that involves training of physical, biological, mathematical, and engineering science students in the importance of science in public policy. The program will involve special activities such as seminars, tours, in addition to coursework and science policy internships. This innovative program will impact students across the University of California system, and help to create a generation of scientists who better appreciate their role in society and in government.

化学催化计划支持加州大学圣地亚哥分校的Seth M.Cohen教授的一个研究项目，该项目将使用合成后修饰(PSM)来改变金属有机骨架(MOF)材料，从而在不破坏MOF的整体结构和孔隙度的情况下引入一系列功能。合成后修饰正在成为获取不能直接制备的功能化MOF的有用工具。这些材料既可用作均相催化剂，也可用作多相催化剂。尽管现在有相当多的MOF被用作多相催化剂的例子，但该提案正确地将催化确定为MOF化学中一个不发达的领域。初步研究表明，PSM可以很容易地将手性取代基、有机催化基团(羧酸、尿素)和金属结合基团引入到MOF中。早期的研究表明，这些修饰的MOF对催化反应是有用的。在国家科学基金会化学部化学催化计划的支持下，科恩博士将进行有助于金属有机骨架(MOF)作为能源、催化和生物医学应用的选择材料的研究。在这些技术应用的基础上，由于MOF的合成后修饰(PSM)的重要性越来越大，Cohen教授的工作引起了MOF社区以外的极大关注。最值得注意的是最近一篇关于通过PSM使用MOF作为固态催化剂的论文(Angew.化学。这在催化学科中引起了极大的关注。这项建议还包括一项新的更广泛的影响/教学活动，以发展科学政策方面的实习和课程作业。位于华盛顿特区的加州大学中心(名为加州大学华盛顿特区分校)的科学政策暑期项目正在创建中。PI是这个新项目的负责人，该项目涉及对物理、生物、数学和工程科学专业的学生进行关于科学在公共政策中的重要性的培训。除了课程作业和科学政策实习外，该计划还将包括研讨会、旅游等特殊活动。这一创新项目将影响整个加州大学系统的学生，并有助于培养更好地认识到他们在社会和政府中的作用的一代科学家。