Selective Extraction Into Fluorous Media

在化学系化学测量和成像项目的支持下，匹兹堡大学的Stephen Weber教授和他的团队正在研究使用选择性分子受体在基质中选择性运输和/或捕获分子，该基质是一种非常差的溶剂。具体来说，该计划设计和测试氟介质（全氟化碳和其他溶质和溶剂溶解在其中）作为选择性提取的基础。 改进的选择性可以打开巨大的可能性？管理分子？在分析、纯化、分离、传感器、智能材料、人类健康、药物输送和合成的关键过程中。这项工作提供了对特氟隆类聚合物的更好理解，使科学家和工程师能够制作改进的薄膜和涂层，用于测量环境，食品，生物系统和工业过程中的化学物质。对新型材料和气体分离的潜在影响也很大。具体目标包括化学？海绵？对全氟辛烷磺酸盐和全氟辛酸盐有很高的选择性，这些物质是河流和溪流中遇到的环境污染物。 参与这项工作的研究生和本科生（包括新生）接触到广泛的化学，提供职业目标的早期定义。

With support from the Chemical Measurement and Imaging Program in the Division of Chemistry, Prof. Stephen Weber and his group at the University of Pittsburgh are studying the selective transport and/or capture of molecules using a selective molecular receptor in a matrix that is a very poor solvent. Specifically, the program devises and tests fluorous media (perfluorocarbons and other solutes and solvents that dissolve in them) as the basis for selective extractions. Improved selectivity can open up tremendous possibilities for ?managing molecules? in processes critical to analysis, purification, separations, sensors, smart materials, human health, drug delivery, and synthesis. The work provides better understanding of Teflon-like polymers, enabling scientists and engineers to make improved films and coatings useful for measuring chemicals in the environment, in foods, in biological systems, and in industrial processes. Potential impact on new types of materials and gas separations is also significant. Specific targets include chemical ?sponges? with high selectivity for perfluorooctane sulfonate and perfluorooctanoate, environmental pollutants encountered in rivers and streams. Graduate and undergraduate students (including freshmen) involved in this work are exposed to a wide range of chemistry, providing early definition of career goals.