Hybrid Dry Cutting - Finish Burnishing of Novel Biodegradable Magnesium-Calcium Implants for Superior Corrosion Performance

混合干切削 - 新型可生物降解镁钙植入物的精加工抛光，具有卓越的腐蚀性能

• 批准号: 1000706
• 负责人: Yuebin Guo
• 金额: $ 33.45万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1000706&HistoricalAwards=false
• 关键词: Hybrid; Dry; Cutting; Finish; Burnishing

The research objective of this award is to test the hypothesis that superior surface integrity enables a significant increase of corrosion resistance of novel biodegradable orthopedic magnesium-calcium implants. The research approach is to adjust surface integrity of magnesium-calcium implants by a new hybrid dry cutting-finish burnishing process. The specific methodology includes: (1) fabrication of biodegradable, biocompatible, and lightweight magnesium calcium alloys via calcium alloying and characterization of dynamic mechanical behaviors and microstructures, (2) creation of desired surface integrity of implants through the novel hybrid dry cutting-finish burnishing process with acoustic emission process monitoring, (3) development of a microscale finite element analysis model to provide a fundamental understanding on the process mechanics and surface integrity, and (4) characterization of process-induced surface integrity and its effect on biodegradation performance in simulated body fluids.The research results will enable progress in biodegradable orthopedic implants via solving the pressing issues of stress shielding and surgical interventions associated with commercial permanent metallic implants. It will provide an insight into the basic relationships between process parameters, surface integrity, and biodegradation performance of orthopedic implants. The benefits to society include the improved life quality and reduced financial burden of the affected individuals. The socioeconomic benefits of biodegradable magnesium-calcium implants will also help boost the competitiveness of the booming medical device manufacturing industry.

该奖项的研究目标是验证这样一个假设，即卓越的表面完整性可以显著提高新型可生物降解的骨科镁钙植入物的耐腐蚀性。研究方法是通过一种新的干切削-抛光混合工艺来调整镁钙植入体的表面完整性。具体的方法包括：(1)通过钙合金化和动态机械行为和微观结构的表征来制造可生物降解的、生物相容的和轻质的镁钙合金，(2)通过具有声发射过程监测的新型干切削-抛光混合工艺来创建所需的植入物表面完整性，(3)开发微尺度有限元分析模型以提供对过程力学和表面完整性的基本理解，以及(4)模拟体液中工艺诱导表面完整性的表征及其对生物降解性能的影响。这些研究成果将通过解决与商业永久金属植入物相关的应力遮挡和手术干预等紧迫问题，使可生物降解整形植入物的发展成为可能。它将提供对骨科植入物的工艺参数、表面完整性和生物降解性能之间的基本关系的洞察。对社会的好处包括改善受影响个人的生活质量和减轻经济负担。可生物降解镁钙植入物的社会经济效益也将有助于提高蓬勃发展的医疗器械制造业的竞争力。