Workshop Proposal: IMAG Futures Meeting

现在是评估生物医学、生物学和行为学研究中建模现状的好时机。2003年，一个小型跨机构工作组成立了机构间建模和分析小组(IMAG)，并首次对生物医学、生物和行为系统进行了机构间公式化规模的建模。那次征集活动资助了24个项目，创建了多尺度建模联盟(MSM)。IMAG MSM联盟现已进入第四个年头，通过最初的MSM征集所颁发的奖项即将到期。从那时起，IMAG的八个政府机构(例如，NIH、NSF、DOE)涌现出许多其他侧重于多尺度建模的倡议。随着原来的MSM项目到期，以及新的MSM项目被引入MSM联盟，IMAG决定今年将取代一年一度的MSM受赠者会议，IMAG将举办一次IMAG未来会议，有20位受邀的生物学广泛思想家代表不同的生物学学科(见附件)，就生物医学、生物和行为建模的未来进行集思广益，包括对当前进展、成功和失败的评估。具体地说，会议将为IMAG提供一个机会，以评估计算建模在多大程度上成功或未能在更广泛的研究工作中产生影响，并在当前生物医学、生物和行为建模的挑战和机遇的背景下讨论这些问题。20名受邀代表不同生物学领域的科学家，以及来自NIH、NSF和美国能源部的代表，将讨论计算对生物学和生物医学的影响，以确定失败和成功，并通过会议产生的报告指导未来的工作。

It is now an opportune time to assess the current state of modeling in biomedical, biological and behavioral research. In 2003, a small trans-agency working group resulted in the formation of the Inter-agency Modeling and Analysis Group (IMAG) and the first inter-agency solicitation formultiscale modeling of biomedical, biological and behavioral systems. That solicitation funded 24 projects, creating the Multiscale Modeling Consortium (MSM). The IMAG MSM Consortium is now in its fourth year and the awards made through the original MSM solicitation are expiring. Since then many other initiatives have emerged from the eight IMAG government agencies thathave a focus on multiscale modeling (e.g., NIH, NSF, DOE). As the original MSM projects expire and new MSM projects are introduced to the MSM Consortium, IMAG has determined that this year, in lieu of the annual MSM grantee meeting, IMAG will hold an IMAG Futures Meeting featuring twenty invited broad thinkers in biology representing different biology disciplines(see attached Agenda) to brainstorm ideas concerning the future of biomedical, biological and behavioral modeling, including an assessment of current progress, both successes and failures. Specifically, the meeting will provide an opportunity for IMAG to assess to what extent computational modeling has succeeded or failed to make a difference in the broader research endeavor, and to discuss these issues in the context of current challenges and opportunities for biomedical, biological and behavioral modeling.The twenty invited scientists representing diverse areas of biology, and representatives from NIH, NSF, and DOE, will discuss the impact of computing on biology and biomedicine to identify failures and successes and direct future work through a report generated from the meeting.