Workshop Proposal: IMAG Futures Meeting
研讨会提案:IMAG 未来会议
基本信息
- 批准号:1008193
- 负责人:
- 金额:$ 1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-12-15 至 2011-11-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
It is now an opportune time to assess the current state of modeling in biomedical, biological and behavioral research. In 2003, a small trans-agency working group resulted in the formation of the Inter-agency Modeling and Analysis Group (IMAG) and the first inter-agency solicitation formultiscale modeling of biomedical, biological and behavioral systems. That solicitation funded 24 projects, creating the Multiscale Modeling Consortium (MSM). The IMAG MSM Consortium is now in its fourth year and the awards made through the original MSM solicitation are expiring. Since then many other initiatives have emerged from the eight IMAG government agencies thathave a focus on multiscale modeling (e.g., NIH, NSF, DOE). As the original MSM projects expire and new MSM projects are introduced to the MSM Consortium, IMAG has determined that this year, in lieu of the annual MSM grantee meeting, IMAG will hold an IMAG Futures Meeting featuring twenty invited broad thinkers in biology representing different biology disciplines(see attached Agenda) to brainstorm ideas concerning the future of biomedical, biological and behavioral modeling, including an assessment of current progress, both successes and failures. Specifically, the meeting will provide an opportunity for IMAG to assess to what extent computational modeling has succeeded or failed to make a difference in the broader research endeavor, and to discuss these issues in the context of current challenges and opportunities for biomedical, biological and behavioral modeling.The twenty invited scientists representing diverse areas of biology, and representatives from NIH, NSF, and DOE, will discuss the impact of computing on biology and biomedicine to identify failures and successes and direct future work through a report generated from the meeting.
现在是评估生物医学、生物学和行为学研究中建模现状的适当时机。2003年,一个小型的跨机构工作组促成了机构间建模和分析小组的成立,并促成了第一个机构间招标公式,即生物医学、生物和行为系统的大规模建模。该招标资助了24个项目,创建了多尺度建模联盟(MSM)。IMAG MSM联盟现在已经是第四个年头了,通过最初的MSM征集所获得的奖项即将到期。从那时起,IMAG的八个政府机构提出了许多其他倡议,这些机构专注于多尺度建模(例如,NIH、NSF、DOE)。由于原有的男男性接触者项目到期,新的男男性接触者项目被介绍给男男性接触者联盟,IMAG决定,今年,代替年度男男性接触者会议,IMAG将举行一次IMAG未来会议,邀请二十位代表不同生物学科的生物学思想家参加(见所附议程)集思广益,探讨生物医学、生物学和行为建模的未来,包括评估目前的进展情况,包括成功和失败。具体而言,会议将为IMAG提供一个机会,评估计算建模在多大程度上成功或失败,在更广泛的研究奋进中发挥作用,并在当前生物医学,生物学和行为建模的挑战和机遇的背景下讨论这些问题。20位受邀的科学家代表生物学的不同领域,以及NIH,NSF和DOE的代表,将讨论计算对生物学和生物医学的影响,以确定失败和成功,并通过会议产生的报告指导未来的工作。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Tamar Schlick其他文献
Nucleosome Clutches in Chromatin are Tightly Regulated by Nucleosome Positions and Linker Histone Density
- DOI:
10.1016/j.bpj.2019.11.3370 - 发表时间:
2020-02-07 - 期刊:
- 影响因子:
- 作者:
Stephanie Portillo;Lucille H. Tsao;Tamar Schlick - 通讯作者:
Tamar Schlick
Biophysical Journal, Volume 99
生物物理学杂志,第 99 卷
- DOI:
- 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
Tamar Schlick - 通讯作者:
Tamar Schlick
Modeling and Simulating RNA: Combining Structural, Dynamic, and Evolutionary Perspectives for Coronavirus Applications
RNA 建模和模拟:结合冠状病毒应用的结构、动态和进化视角
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:0
- 作者:
Tamar Schlick;Shuting Yan - 通讯作者:
Shuting Yan
Techniques for and challenges in reconstructing 3D genome structures from 2D chromosome conformation capture data
从二维染色体构象捕获数据重建三维基因组结构的技术和挑战
- DOI:
10.1016/j.ceb.2023.102209 - 发表时间:
2023-08-01 - 期刊:
- 影响因子:4.300
- 作者:
Zilong Li;Stephanie Portillo-Ledesma;Tamar Schlick - 通讯作者:
Tamar Schlick
Structural Bioinformatics : RAGPOOLS : RNA-As-Graph-Pools – A Web Server for Assisting the Design of Structured RNA Pools for In Vitro Selection
结构生物信息学:RAGPOOLS:RNA-As-Graph-Pools – 用于协助设计用于体外选择的结构化 RNA 库的 Web 服务器
- DOI:
- 发表时间:
2007 - 期刊:
- 影响因子:0
- 作者:
N. Kim;Jin Sup Shin;Shereef Elmetwaly;H. H. Gan;Tamar Schlick - 通讯作者:
Tamar Schlick
Tamar Schlick的其他文献
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{{ truncateString('Tamar Schlick', 18)}}的其他基金
MFB: RNA modifications of frameshifting stimulators: cellular platforms to engineer gene expression by computational mutation predictions and functional experiments
MFB:移码刺激器的RNA修饰:通过计算突变预测和功能实验来设计基因表达的细胞平台
- 批准号:
2330628 - 财政年份:2024
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
Collaborative Research: Unraveling Structural and Mechanistic Aspects of RNA Viral Frameshifting Elements by Graph Theory and Molecular Modeling
合作研究:通过图论和分子建模揭示RNA病毒移码元件的结构和机制
- 批准号:
2151777 - 财政年份:2022
- 资助金额:
$ 1万 - 项目类别:
Continuing Grant
RAPID: Exploring Covid-19 RNA Viral Targets By Graph-Theory-Based Modeling
RAPID:通过基于图论的建模探索 Covid-19 RNA 病毒靶点
- 批准号:
2030377 - 财政年份:2020
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
Computational Methods for Tertiary RNA Folding and Novel RNA Design
RNA 三级折叠和新型 RNA 设计的计算方法
- 批准号:
0727001 - 财政年份:2007
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
Simulating Large-Scale Conformational Rearrangements and Reaction Kinetics Profiles in DNA Polymerase Beta to Interpret DNA Synthesis Fidelity Mechanisms
模拟 DNA 聚合酶 Beta 中的大规模构象重排和反应动力学曲线,以解释 DNA 合成保真度机制
- 批准号:
0316771 - 财政年份:2003
- 资助金额:
$ 1万 - 项目类别:
Continuing Grant
Toward RNA Genomics: A Pilot Study in the Analysis, Design, and Prediction of RNA Structures
RNA 基因组学:RNA 结构分析、设计和预测的初步研究
- 批准号:
0201160 - 财政年份:2002
- 资助金额:
$ 1万 - 项目类别:
Continuing Grant
International Workshop: Methods for Macromolecular Modeling
国际研讨会:大分子建模方法
- 批准号:
0071877 - 财政年份:2000
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
Postdoc: Brownian Dynamics of DNA Slithering
博士后:DNA滑动的布朗动力学
- 批准号:
9704681 - 财政年份:1997
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
New Algorithms for Large Time-Step Molecular Dynamics Simulations and their Application to Protein and Nucleic Acids
大时间步长分子动力学模拟的新算法及其在蛋白质和核酸中的应用
- 批准号:
9310295 - 财政年份:1993
- 资助金额:
$ 1万 - 项目类别:
Standard Grant
PYI: Computation of Macromolecular Structure
PYI:高分子结构的计算
- 批准号:
9157582 - 财政年份:1991
- 资助金额:
$ 1万 - 项目类别:
Continuing Grant
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