Nanocapsules

化学系的大分子、超分子和纳米化学计划支持曾傑瑞·L·阿特伍德教授在纳米胶囊设计和合成领域的工作。这项研究的目标包括：(1)合成金属离子配位缝合的新胶囊；(2)跨胶囊壁的传输；(3)合成超大型纳米胶囊；(4)金属离子配位缝合的管状组件。对纳米胶囊组装中涉及的自组装过程的了解的增加将对金属离子诱导的自组装的其他领域产生影响。此外，各种尺寸胶囊的开发将为在受限环境中进行化学反应提供新的容器。从胶囊到管子的研究涉及自组装过程的逻辑发展，自组装过程以形成胶囊而终止，基本上在一个维度上无限延伸。除了提供新的基础知识外，这项关于纳米胶囊的研究还为靶向药物输送和催化等实际应用提供了机会。此外，本研究还有助于科学人力资源的开发。参与该项目的本科生、研究生和博士后研究员将接受培训，以便在理解此类基础研究是以目标为导向的情况下推进研究。

The Macromolecular, Supramolecular and Nanochemistry (MSN) Program of the Division of Chemistry supports the work of Professor Jerry L. Atwood in the area of nanocapsule design and synthesis. The objectives of this research include: (1) the synthesis of new capsules seamed by metal-ion coordination; (2) transport across capsule walls; (3) the synthesis of very large nanocapsules and (4) tube assemblies seamed by metal-ion coordination. The increased understanding of the self-assembly process involved in the nanocapsule assembly will have ramifications in other areas of metal-ion induced self-assembly. In addition, the development of capsules over a range of sizes will provide new containers for carrying out chemical reactions in constrained environments. The extension of the research from capsules to tubes involves a logical development of the self-assembly process which terminates with the formation of a capsule to that which extends essentially infinitely in one dimension. In addition to providing new fundamental knowledge, this research on nanocapsules presents opportunities for practical applications such as targeted drug delivery and catalysis. Furthermore, this research contributes to the development of human resources in sciences. The undergraduate students, the graduate students, and the postdoctoral fellows involved in this program will be trained to carry the research forward with the understanding that such basic research is goal oriented.