Nanocapsules

纳米胶囊

• 批准号: 1012998
• 负责人: Jerry Atwood
• 金额: $ 39万
• 依托单位: University of Missouri-Columbia
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1012998&HistoricalAwards=false
• 关键词: Nanocapsules

The Macromolecular, Supramolecular and Nanochemistry (MSN) Program of the Division of Chemistry supports the work of Professor Jerry L. Atwood in the area of nanocapsule design and synthesis. The objectives of this research include: (1) the synthesis of new capsules seamed by metal-ion coordination; (2) transport across capsule walls; (3) the synthesis of very large nanocapsules and (4) tube assemblies seamed by metal-ion coordination. The increased understanding of the self-assembly process involved in the nanocapsule assembly will have ramifications in other areas of metal-ion induced self-assembly. In addition, the development of capsules over a range of sizes will provide new containers for carrying out chemical reactions in constrained environments. The extension of the research from capsules to tubes involves a logical development of the self-assembly process which terminates with the formation of a capsule to that which extends essentially infinitely in one dimension. In addition to providing new fundamental knowledge, this research on nanocapsules presents opportunities for practical applications such as targeted drug delivery and catalysis. Furthermore, this research contributes to the development of human resources in sciences. The undergraduate students, the graduate students, and the postdoctoral fellows involved in this program will be trained to carry the research forward with the understanding that such basic research is goal oriented.

化学系的大分子、超分子和纳米化学（MSN）项目支持Jerry L. Atwood教授在纳米胶囊设计和合成领域的工作。本研究的目的包括：(1)合成新型金属离子配位胶囊；(2)跨囊壁运输；(3)超大纳米胶囊的合成和(4)金属离子配位缝合的管组件。对纳米胶囊组装过程中自组装过程的进一步了解将对金属离子诱导自组装的其他领域产生影响。此外，各种尺寸胶囊的开发将为在受限环境中进行化学反应提供新的容器。从胶囊到管的研究延伸涉及自组装过程的逻辑发展，该过程终止于胶囊的形成，在一维上基本上无限延伸。除了提供新的基础知识外，这项关于纳米胶囊的研究为实际应用提供了机会，例如靶向药物输送和催化。此外，该研究有助于科学人力资源的开发。本项目所涉及的本科生、研究生和博士后将在理解这些基础研究是目标导向的前提下进行研究。