Hosts for Anion Binding and Fullerene Complexation

在有机动力学项目的支持下，密苏里-哥伦比亚大学化学系的曾傑瑞·L·阿特伍德教授进行了旨在结合阴离子和复杂富勒烯的宿主化合物的合成。对杯(4)芳烃、杯(5)芳烃和环三氢韦拉烯的研究有助于从根本上理解影响阴离子结合的因素。通过多种自组装工艺构建的金属深腔模拟材料的发展提供了增强的阴离子结合剂。杯芳烃和环三氢呋喃主体的合成旨在满足特定富勒烯的大小、形状和静电要求，这为设计富勒烯选择性络合剂提供了机会。近年来，关于中性分子和带正电荷的离子可能被专门为此目的设计的分子识别和结合的方式的研究迅速增长。这类研究具有广泛的影响，包括在理解生物系统中关键的分子-分子和分子-离子相互作用方面的进展，以及为分离和提纯材料开发实用方法。相比之下，负电荷离子结合的相应进展相对较慢。密苏里-哥伦比亚大学化学系的曾傑瑞·L·阿特伍德教授在有机动力学计划的支持下，合成了旨在通过特定化学作用组合识别和结合阴离子的有机分子。相关系统提供了实现对各种富勒烯(巴克球)的类似识别的机会，为进一步了解分子-分子相互作用的性质以及分离和提纯富勒烯家族的各种成员的技术提供了进一步的见解。

With the support of the Organic Dynamics Program, Professor Jerry L. Atwood, of the Department of Chemistry at the University of Missouri - Columbia, carries out the synthesis of host compounds designed to bind anions and to complex fullerenes. Studies of calix(4)arenes, calix(5)arenes, and cyclotriveratrylenes which have been metallated on the outer pi faces contribute to a fundamental understanding of the factors influencing the binding of anions. Development of metallated deep cavity analogs, which are constructed by versatile self-assembly processes, affords enhanced anion binding agents. Synthesis of calixarene and cyclotriveratrylene hosts designed to match the size, shape, and electrostatic requirements of specific fullerenes offer the opportunity to devise fullerene-selective complexing agents. Recent years have seen rapid growth in studies of the ways in which neutral molecules and positively-charged ions may be specifically recognized and bound by molecules designed for this purpose. Such studies have had a wide range of implications, including advances in understanding of critical molecule-molecule and molecule-ion interactions in biological systems as well as development of practical methods for the separation and purification of materials. Corresponding developments for the binding of negatively-charged ions, in contrast, have been comparatively slow to appear. Professor Jerry L. Atwood, of the Department of Chemistry at the University of Missouri - Columbia, with the support of the Organic Dynamics Program, synthesizes organic molecules designed to recognize and bind anions through a combination of specific chemical interactions. Related systems offer the opportunity to effect analogous recognition of various fullerenes (`Buckyballs`), providing further insights into the nature of molecule-molecule interaction as well as techniques for the separation and purification of various members of the fullerene family.