2010 FASEB Summer Conference on the Biology of Integrated Nuclear and Extranuclear Steroid Signaling. Conference Program August 8 - 12, 2010, Aspen Snowmass, CO

雌激素、孕激素、睾酮和皮质醇等类固醇激素的合成、释放和作用对正常的日常生活至关重要。例如，皮质醇的缺乏与生活不相容，女性雌激素分泌不足会导致潮热、骨质疏松和不孕不育。此外，类固醇还会促进某些癌症的生长。这次会议的目的是将研究类固醇激素对大脑和其他器官系统(心脏、胰腺、性腺、结肠等)影响的世界知名科学家聚集在一起。首要目标是开发广泛的新概念，了解类固醇如何对不同器官系统中的单个细胞产生直接影响，以及对器官系统的生长和发育产生长期影响。这次会议不仅将促进该领域专家之间的新合作，还将为具有不同背景的初级科学家提供一个与这些专家领导人互动和合作的场所。此外，FASE B会议将促进新的系统级生物学方法的发展，以了解通信网络(通过血液、神经等)。参与全身的类固醇活动。这群杰出的科学家，包括研究简单海洋生物的海洋生物学家和治疗病人的医生之间的相互作用，将允许开发共同的研究方法，以更好地了解内分泌系统。

The synthesis, release and actions of steroid hormones such as estrogens, progesterone, testosterone, and cortisol are vital for normal daily living. For example, the absence of cortisol production is incompatible with life, and insufficient estrogen production in women leads to hot flashes, osteoporosis and infertility. In addition, steroids promote the growth of some cancers. The purpose of this conference is to bring together world-renowned scientists studying the effects of steroid hormones in the brain and other organ systems (heart, pancreas, gonads, colon, etc.). The overarching goal is to develop broad new concepts about the way in which steroids have immediate impact on individual cells in various organ systems as well as long term effects on growth and development of organ systems. This meeting will not only foster new collaborations among the experts in the field but will also provide a venue for junior scientists of diverse background to interact and collaborate with these expert leaders. Moreover, the FASEB conference will foster the development of novel systems level biological approaches toward understanding the communication networks (via blood, nerves, etc.) involved in steroid actions throughout the body. The cross-talk between this distinguished group of scientists, which include marine biologists that work on simple marine organisms and physicians that treat patients, will allow the development of common research approaches to better understand endocrine systems.