2010 FASEB Summer Conference on the Biology of Integrated Nuclear and Extranuclear Steroid Signaling. Conference Program August 8 - 12, 2010, Aspen Snowmass, CO

类固醇激素（如雌激素、黄体酮、睾酮和皮质醇）的合成、释放和作用对正常的日常生活至关重要。例如，皮质醇分泌不足与生活格格不入，女性雌激素分泌不足会导致潮热、骨质疏松和不孕。此外，类固醇还会促进某些癌症的生长。这次会议的目的是汇集世界知名的科学家，研究类固醇激素在大脑和其他器官系统（心脏、胰腺、性腺、结肠等）中的作用。总体目标是发展关于类固醇对各种器官系统中单个细胞的直接影响以及对器官系统生长和发育的长期影响的方式的广泛的新概念。这次会议不仅将促进该领域专家之间的新合作，而且还将为不同背景的青年科学家提供一个与这些专家领导人进行互动和合作的场所。此外，FASEB会议将促进新的系统级生物学方法的发展，以理解涉及全身类固醇作用的通信网络（通过血液，神经等）。这群杰出的科学家之间的交流，包括研究简单海洋生物的海洋生物学家和治疗病人的医生，将有助于发展共同的研究方法，以更好地了解内分泌系统。

The synthesis, release and actions of steroid hormones such as estrogens, progesterone, testosterone, and cortisol are vital for normal daily living. For example, the absence of cortisol production is incompatible with life, and insufficient estrogen production in women leads to hot flashes, osteoporosis and infertility. In addition, steroids promote the growth of some cancers. The purpose of this conference is to bring together world-renowned scientists studying the effects of steroid hormones in the brain and other organ systems (heart, pancreas, gonads, colon, etc.). The overarching goal is to develop broad new concepts about the way in which steroids have immediate impact on individual cells in various organ systems as well as long term effects on growth and development of organ systems. This meeting will not only foster new collaborations among the experts in the field but will also provide a venue for junior scientists of diverse background to interact and collaborate with these expert leaders. Moreover, the FASEB conference will foster the development of novel systems level biological approaches toward understanding the communication networks (via blood, nerves, etc.) involved in steroid actions throughout the body. The cross-talk between this distinguished group of scientists, which include marine biologists that work on simple marine organisms and physicians that treat patients, will allow the development of common research approaches to better understand endocrine systems.