2010 FASEB Summer Conference on the Biology of Integrated Nuclear and Extranuclear Steroid Signaling. Conference Program August 8 - 12, 2010, Aspen Snowmass, CO

2010 年 FASEB 夏季综合核和核外类固醇信号传导生物学会议。

• 批准号: 1019920
• 负责人: Martin Kelly
• 金额: $ 4.4万
• 依托单位: Federation of Amer Societies For Exper Biology
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1019920&HistoricalAwards=false
• 关键词: 2010; FASEB; Summer; Conference; Biology

The synthesis, release and actions of steroid hormones such as estrogens, progesterone, testosterone, and cortisol are vital for normal daily living. For example, the absence of cortisol production is incompatible with life, and insufficient estrogen production in women leads to hot flashes, osteoporosis and infertility. In addition, steroids promote the growth of some cancers. The purpose of this conference is to bring together world-renowned scientists studying the effects of steroid hormones in the brain and other organ systems (heart, pancreas, gonads, colon, etc.). The overarching goal is to develop broad new concepts about the way in which steroids have immediate impact on individual cells in various organ systems as well as long term effects on growth and development of organ systems. This meeting will not only foster new collaborations among the experts in the field but will also provide a venue for junior scientists of diverse background to interact and collaborate with these expert leaders. Moreover, the FASEB conference will foster the development of novel systems level biological approaches toward understanding the communication networks (via blood, nerves, etc.) involved in steroid actions throughout the body. The cross-talk between this distinguished group of scientists, which include marine biologists that work on simple marine organisms and physicians that treat patients, will allow the development of common research approaches to better understand endocrine systems.

类固醇激素如雌激素、孕酮、睾酮和皮质醇的合成、释放和作用对正常的日常生活至关重要。 例如，皮质醇生产的缺乏与生活不相容，女性雌激素生产不足会导致潮热，骨质疏松和不孕症。 此外，类固醇促进某些癌症的生长。这次会议的目的是汇集世界知名的科学家研究类固醇激素在大脑和其他器官系统（心脏，胰腺，性腺，结肠等）的影响。总体目标是发展广泛的新概念，即类固醇对各种器官系统中的单个细胞产生直接影响的方式，以及对器官系统生长和发育的长期影响。这次会议不仅将促进该领域专家之间的新合作，还将为不同背景的年轻科学家提供一个与这些专家领导人互动和合作的场所。此外，FASEB会议将促进开发新的系统级生物学方法，以了解通信网络（通过血液，神经等）。参与类固醇在全身的作用。 这一杰出的科学家群体包括研究简单海洋生物的海洋生物学家和治疗患者的医生，他们之间的对话将有助于开发共同的研究方法，以更好地了解内分泌系统。