Arabidopsis 2010: Analysis of the Cytokinin-Regulated Transcriptional Network

拟南芥 2010：细胞分裂素调控转录网络的分析

• 批准号: 1022053
• 负责人: Joseph Kieber
• 金额: $ 365.88万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1022053&HistoricalAwards=false
• 关键词: Arabidopsis; 2010; Analysis; Cytokinin; Regulated

Cytokinins are plant hormones that affect a diverse array of plant growth and development processes. How cytokinins mediate such a diverse array of processes remains a fundamental question in plant biology with important agricultural implications. In this project, genetic, molecular, and genomic approaches will be used to identify and characterize the critical factors that control gene expression in response to cytokinin. Computational approaches will then be used to build a network of cytokinin-regulated gene expression. These data will be incorporated into a database available through the project website (http://www.bio.unc.edu/research/two-component/default.htm) so that the research community can easily view and make use of the regulatory network. Results from the proposed research will benefit society through the elucidation of a critical gene network that regulates multiple traits of agronomic importance. Previous work suggests that results from the project will provide avenues to modify agriculturally relevant traits such as grain yield, energy capture and use, senescence, responses to environmental stresses, and patterns of growth and development. The proposed research will enhance the infrastructure of research and education by providing training for undergraduate students, graduate students, and post-doctoral researchers, as well as the creation and maintenance of programs aimed at fostering science education in grades K-12.

细胞分裂素是一种影响多种植物生长发育过程的植物激素。细胞分裂素如何调节如此多样化的过程仍然是植物生物学中的一个基本问题，具有重要的农业意义。在这个项目中，将使用遗传、分子和基因组方法来识别和表征控制细胞分裂素反应的基因表达的关键因素。然后将使用计算方法来构建细胞分裂素调节的基因表达网络。这些数据将被纳入通过项目网站(http://www.bio.unc.edu/research/two-component/default.htm)提供的数据库，以便研究界可以轻松地查看和利用监管网络。这项拟议研究的结果将通过阐明调节多种重要农艺性状的关键基因网络而造福于社会。先前的工作表明，该项目的结果将为改变与农业相关的性状提供途径，如谷物产量、能量捕获和利用、衰老、对环境压力的反应以及生长和发育模式。拟议的研究将通过为本科生、研究生和博士后研究人员提供培训，以及创建和维护旨在促进K-12年级科学教育的项目，来加强研究和教育的基础设施。