Separating Science from Fiction: Introducing Liquid Chromatography in an Undergraduate Laboratory Curriculum

将科学与虚构分开：在本科实验室课程中引入液相色谱法

• 批准号: 1044365
• 负责人: Christopher Palmer
• 金额: $ 17万
• 依托单位: University of Montana
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1044365&HistoricalAwards=false
• 关键词: Separating; Science; Fiction; Introducing; Liquid

The major goal of the project is to provide chemistry and biochemistry students with the fundamental understanding and practical experience necessary to be successful in their future careers. One effective means for doing this is through introduction of modern chemical instrumentation early and throughout the chemistry and biochemistry curricula. This project develops laboratory exercises of increasing sophistication that utilize four liquid chromatography systems with varying capabilities. Chromatography is an important enabling instrumental method that is used in various forms across the chemical and biochemical disciplines for a wide variety of applications, including pharmaceutical, food, environmental and biomedical analyses and studies. The exercises begin with illustrative bench top exercises and culminate with hands-on experience. Exercises of increasing sophistication are being implemented in laboratories at all levels of the curriculum, such that students who complete the curriculum have a strong working knowledge of this important technology. An important aspect of this project is the implementation of liquid chromatography exercises in large-enrollment laboratory courses like those taught at most intermediate or large universities. This is accomplished through early instruction using illustrative bench top exercises and through application of multiple state-of-the-art yet affordable separations instruments that allow fast separations. The project is also introducing the technology to local high school science teachers through workshops. In addition, high school students that utilize the instrumentation are being supported to attend local and regional science fairs.

该项目的主要目标是为化学和生物化学学生提供在未来职业生涯中取得成功所需的基本理解和实践经验。这样做的一个有效手段是通过引入现代化学仪器早期和整个化学和生物化学课程。该项目开发了越来越复杂的实验室练习，利用四个不同能力的液相色谱系统。色谱法是一种重要的仪器方法，以各种形式在化学和生物化学学科中用于各种应用，包括制药，食品，环境和生物医学分析和研究。练习开始与说明板凳上的练习，并与实践经验达到高潮。在各级课程的实验室中正在实施越来越复杂的练习，以便完成课程的学生对这一重要技术有很强的工作知识。该项目的一个重要方面是在大规模招生的实验室课程中实施液相色谱练习，如大多数中等或大型大学所教授的课程。这是通过使用说明性台式练习的早期指导和通过应用多个最先进但价格合理的分离仪器来实现的，这些仪器允许快速分离。该项目还通过研讨会向当地高中科学教师介绍这项技术。此外，正在支持使用仪器的高中学生参加地方和区域科学博览会。