MRI: Acquisition of a LSM710 Laser Scanning Confocal Microscope to Enhance Plant Research and Training at the University of North Texas

MRI：购买 LSM710 激光扫描共焦显微镜以加强北德克萨斯大学的植物研究和培训

• 批准号: 1126205
• 负责人: Jyoti Shah
• 金额: $ 37.73万
• 依托单位: University of North Texas
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1126205&HistoricalAwards=false
• 关键词: MRI; Acquisition; LSM710; Laser; Scanning

This MRI award funds the acquisition of a LSM710 laser scanning confocal microscope tosupport research and training in plant signaling at the University of North Texas by providingimaging capabilities that are required for molecular and biochemical studies at the cellular andsub-cellular levels. In addition, the confocal microscope will enhance research and training indevelopmental physiology, eco-toxicology, neurobiology and microbiology. The LSM710 willcome equipped with a 34-channel spectral detector that will facilitate studying the in situexpression pattern of genes, intracellular protein localization and protein-protein interactions,changes in Ca2+, reactive oxygen species and sugar fluxes, and macromolecular dynamics.Broader Impacts: The LSM710 will benefit undergraduate and graduate students and post-docsby providing them training in the application of imaging technology for research anddevelopment. The confocal microscope will also provide opportunities to encourage andbroaden the participation and training in the Life Sciences of underrepresented minorities, highschool-aged students and future secondary teachers through the McNair program, the TeachNorth Texas program, the Texas Academy of Mathematics and Science, the Honors College, theNSF S-STEM supported (#0807128) Fostering Outstanding Cohorts in Undergraduate Science(FOCUS) Scholarships program, and the Howard Hughes Medical Institute UndergraduateScience Education program at the University of North Texas. The LSM710 will supportresearch by these students. The instrument will positively impact the environment and societyby supporting research on the discovery, function and application of signaling mechanisms inplants, which will augment sustainable agriculture, industry and renewable natural resources.

该 MRI 奖项资助购买 LSM710 激光扫描共焦显微镜，通过提供细胞和亚细胞水平的分子和生化研究所需的成像功能，支持北德克萨斯大学植物信号传导的研究和培训。此外，共焦显微镜将加强发育生理学、生态毒理学、神经生物学和微生物学方面的研究和培训。 LSM710 将配备 34 通道光谱检测器，有助于研究基因的原位表达模式、细胞内蛋白质定位和蛋白质-蛋白质相互作用、Ca2+ 的变化、活性氧和糖通量以及大分子动力学。更广泛的影响：LSM710 将为本科生、研究生和博士后提供培训，使他们受益 成像技术的应用进行研究和开发。共焦显微镜还将通过 McNair 计划、TeachNorth Texas 计划、德克萨斯州数学与科学学院、荣誉学院、NSF S-STEM 支持的 (#0807128) 培养本科科学杰出群体 (FOCUS) 提供机会，鼓励和扩大代表性不足的少数族裔、高中生和未来中学教师的生命科学参与和培训 奖学金计划以及北德克萨斯大学霍华德休斯医学院本科科学教育计划。 LSM710 将支持这些学生的研究。该仪器将通过支持植物信号机制的发现、功能和应用研究，对环境和社会产生积极影响，这将增强可持续农业、工业和可再生自然资源。