Making the Arabidopsis Biological Resource Center Business Model Possible

让拟南芥生物资源中心商业模式成为可能

• 批准号: 1143813
• 负责人: Erich Grotewold
• 金额: $ 57.36万
• 依托单位: Ohio State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-15 至 2016-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1143813&HistoricalAwards=false
• 关键词: Making; Arabidopsis; Biological; Resource; Center

Intellectual MeritThe Arabidopsis Biological Resource Center (ABRC) was established in 1991 and supported since by NSF through five-year grants. The ABRC collects, preserves, reproduces and distributes diverse seed and DNA stocks of Arabidopsis thaliana and related species. Information and ordering services for the distributed resources are maintained by The Arabidopsis Information Resource (TAIR; http://arabidopsis.org/). The ABRC serves a dynamic community of plant researchers with a common goal to understand the basic processes of flowering plants, as well as to apply this understanding to further crop improvement. The activity of the Center is essential towards full-filling the community goal of having multiple mutant alleles for every one of the Arabidopsis ~27,000 genes. Approximately 10,000 registered users in TAIR utilize the Center by ordering close to 100,000 stocks annually from a collection of approximately 1,000,000 stocks, equally distributed between seeds and DNA. The impact of the ABRC is represented by a significant contribution to hundreds of articles by the Arabidopsis community in high-impact journals each year. Stock donation and demand continues to grow and is likely to remain high for the foreseeable future. Here, the ABRC requests funds to upgrade and increase the capacity and efficiency of the DNA and seed-handling operations. Specifically, funds are requested for a cold dry room with a specialized rack system for short and long-term seed storage, for a specialized -20 C freezer for very long-term seed storage, a robotic system for increased output in DNA stock operations, and a soil handler to increase planting reproducibility and efficiency. These equipment pieces are central to the realization of a Business Model in which ABRC becomes significantly more independent from NSF support in its operations.Broader ImpactsRealizing the strategic position of the ABRC in the Arabidopsis and plant community, the Center started a pilot program to harness the know-how and stocks at the ABRC to enhance the awareness and visibility of plants in K-12. Towards this objective, ABRC personnel developed a three-module research project entitled "Greening the Classroom: Arabidopsis thaliana as a tool to teach plant genetics", the relationship of plants with the environment, and plant development for high-school students". This plan is currently being implemented in high-schools in the Columbus City School district, and will be expanded to a number of other schools in Ohio. This effort is supported by the Curriculum Quality Control Council of Columbus City Schools (http://www.columbus.k12.oh.us), which included the "Greening the Classroom" initiative in the official curriculum of CCS. In addition, the ABRC participated in the organization of the second Plant Functional Genomics Workshop (http://www.biosci.ohiostate.edu/workshop/). This workshop offered a hands-on practical experience combined with lectures by leaders in the field to ~20 participants (high-school teachers, undergrads, Ph.D. students, postdocs and junior faculty members) from all over the world. These educational initiatives are significantly complementing the sustained and highly-valued community service mission of the ABRC, thus increasing the appreciation for Arabidopsis and plants in general in our younger generations.Co-funded by the Divisions of Molecular and Cellular Biosciences, Integrative Organismal Systems, and Biological Infrastructure.

知识分子优点拟南芥生物资源中心（ABRC）于1991年成立，自NSF至五年赠款以来就得到了支持。 ABRC收集，蜜饯，再现和分发拟南芥及相关物种的种子和DNA种群。分布式资源的信息和订购服务由拟南芥信息资源（Tair; http://arabidopsis.org/）维护。 ABRC为植物研究人员的动态社区提供了一个共同的目标，以了解开花植物的基本过程，并将这种理解应用于进一步的作物改善。该中心的活动对于整个社区目标的全面目标至关重要，即拟南芥中的每个基因中的每个基因都有多个突变等位基因。 Tair中大约有10,000名注册用户通过每年从大约1,000,000股股票中订购近100,000股股票来利用该中心，同样分配在种子和DNA之间。 ABRC的影响是每年在高影响力期刊上对拟南芥社区对数百篇文章做出的重大贡献。股票捐赠和需求不断增长，在可预见的将来可能会保持较高的状态。在这里，ABRC要求资金升级并提高DNA和种子处理操作的能力和效率。具体而言，要求资金用于带有专门架子系统的冷干室，用于短期和长期种子存储，用于长期储存的专业-20 c冰箱，一种用于增加DNA库存操作的机器人系统，以及提高种植可再现性和效率的土壤处理程序。这些设备的作品是实现业务模型的核心，在该模型中，ABRC在其运营中与NSF支持更加独立。BoaderImplass Implasts将ABRC在拟南芥和植物社区中的战略地位进行了影响，该中心启动了一项试点计划，以利用知识和ABRC的股票，以增强K-112植物的认识和可见性。朝向这一目标，ABRC人员开发了一个三个模块研究项目，标题为“教室：拟南芥，作为教授植物遗传学的工具”，植物与环境的关系以及高中生的植物开发。该计划目前正在哥伦布城市学区的高中委员会中实施，该委员会的竞争将在哥伦布城市学区的高级委员会进行，这将扩展到其他范围，以实现其他效果。哥伦布市学校（http://www.columbus.k12.oh.us），其中包括CC的官方课程的“绿色教室”计划。动手实践经验以及该领域的领导者的讲座，为20名参与者（高中老师，本科生，博士学位，博士学位，博士后和初级教师），这些教育计划从全世界各地都显着补充，从而使艾伯特（Abrc）的社区服务与艾伯特（Abrc）相互补充。分子和细胞生物科学，综合生物系统和生物基础设施的组成。