Resolving rapid radiations and recent speciation in North American spiny lizards (Sceloporus)

解决北美刺蜥蜴（Sceloporus）的快速辐射和近期物种形成问题

• 批准号: 1144630
• 负责人: Adam Leache
• 金额: $ 47.1万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1144630&HistoricalAwards=false
• 关键词: Resolving; rapid; radiations; recent; speciation

Understanding rapid bursts of speciation requires new phylogenetic methods as well as large data sets. In this project, the investigators will study a group of lizards (genus Sceloporus) to resolve rapid radiations and recent speciation events in the tree of life. The accumulation of new species over brief time intervals characterizes both of these events, which are challenging to elucidate because they leave limited genetic signatures across the genome. The investigators will apply new DNA sequencing technologies to investigate rapid speciation; determine the feasibility of analyzing extremely large genomic datasets using new models; and stress-test inference methods to identify the analytical upper limits of dataset size and complexity.Promoting the progress of science and the integration of research and education will involve four activities: 1) education and public outreach at The Burke Museum of Natural History and Culture, including a new public exhibit on the integration of genomics and natural history research, 2) postdoctoral mentoring, 3) undergraduate and graduate student training, and 4) the acquisition and dissemination of new comparative genomics data. Lizards in the North American genus Sceloporus are prominent in comparative studies of ecology, physiology, life history evolution, and chromosome evolution. This organismal research will yield a robust new estimate of the evolutionary history of these lizards, a valuable commodity for the comparative biology community.

了解物种形成的快速爆发需要新的系统发育方法以及大量的数据集。在这个项目中，研究人员将研究一组蜥蜴（Sceloporus属），以解决生命树中的快速辐射和最近的物种形成事件。新物种在短时间间隔内的积累是这两个事件的特征，这两个事件很难阐明，因为它们在基因组中留下了有限的遗传特征。研究人员将应用新的DNA测序技术来研究快速物种形成;确定使用新模型分析超大型基因组数据集的可行性;以及压力测试推理方法来确定数据集大小和复杂性的分析上限。促进科学进步和研究与教育的融合将涉及四项活动：1）伯克自然历史和文化博物馆的教育和公共宣传，包括关于基因组学和自然历史研究整合的新公共展览，2）博士后指导，3）本科生和研究生培训，以及4）新的比较基因组学数据的获取和传播。北美盾孔菌属（Sceloporus）植物在生态学、生理学、生活史进化和染色体进化等方面的比较研究中占有重要地位。这项生物研究将对这些蜥蜴的进化历史产生一个强有力的新估计，这对比较生物学界来说是一件有价值的商品。