Collaborative Research: Epidermal gland evolution and the origins of structural and chemical signaling diversity

合作研究:表皮腺进化以及结构和化学信号多样性的起源

基本信息

  • 批准号:
    1855845
  • 负责人:
  • 金额:
    $ 48.88万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-12-01 至 2024-11-30
  • 项目状态:
    已结题

项目摘要

Animal communication systems have evolved an extraordinarily varied set of morphological and physiological structures and signals in order to control essential behavioral interactions, such as individual recognition, establishment of social hierarchies, territoriality, and intersexual selection. Visual, acoustic, and chemical signaling modes allow for complex repertoires of behavioral displays, yet little is known of how communication systems originated and evolved in most species in the animal tree of life, including reptiles. This project aims to fill this important gap by investigating the origin and evolution of novel communication mechanisms (epidermal glands) in lizards and how such systems are shaped by ecological and environmental parameters. Results from this research will provide a framework for predicting how human-induced environmental changes could impact chemical signaling. This project converges with NSF priorities for both science and society by expanding natural history collections and genetic resources in the U.S., building large data sets for comparative studies, developing new teaching materials focused on chemical communication, and directly contributing to scientific education and public outreach with the development of a new public exhibit at the Burke Museum of Natural History and Culture.Among lizards and snakes, chemical signaling has been increasingly acknowledged as a critical, yet underappreciated, component of communication. This project will use integrative methods and tools, including advanced imaging, biochemistry, phylogenetics, and gene expression across diverse lizard groups from North America, South America, and Africa to investigate the evolution of novel epidermal glands that are crucial in mediating behavioral interactions on several groups of lizards. This project will test several hypotheses with the diverse datatypes collected over the course of the research, including (1) chemical differences between species correlate with environmental parameters and structural complexity of the habitats and microhabitats; (2), major transitions in the presence or absence of epidermal glands and chemical signals across the lizard tree of life track shifts in habitat/microhabitat (such as changes in temperature, humidity, and solar radiation preferences); (3) independent origins of epidermal glands across the lizard tree of life share a common genetic origin, providing strong evidence that such structures share deep and common ancestry. By using lizard epidermal glands as our study system, this project will provide insight into the evolution of novelty and those structures that play important roles in communication and behavior.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
动物交流系统已经进化出一套非常多样化的形态和生理结构和信号,以控制基本的行为相互作用,如个体识别,建立社会等级,领土和间性选择。视觉、听觉和化学信号模式允许复杂的行为展示,但人们对动物生命树中大多数物种(包括爬行动物)的通信系统如何起源和进化知之甚少。该项目旨在通过调查蜥蜴中新的通信机制(表皮腺体)的起源和进化以及这些系统如何受生态和环境参数的影响来填补这一重要空白。这项研究的结果将为预测人类引起的环境变化如何影响化学信号提供一个框架。该项目通过扩大美国的自然历史收藏和遗传资源,与NSF在科学和社会方面的优先事项趋同,建立大型数据集进行比较研究,开发新的教学材料,重点是化学通信,并直接促进科学教育和公共宣传与伯克自然历史和文化博物馆的一个新的公共展览的发展。在蜥蜴和蛇,化学信号已越来越多地被认为是一个关键的,但未得到充分重视,通信的组成部分。该项目将使用综合方法和工具,包括先进的成像,生物化学,遗传学和来自北美,南美和非洲的不同蜥蜴群体的基因表达,以研究新型表皮腺体的进化,这些腺体在介导几组蜥蜴的行为相互作用中至关重要。本项目将利用研究过程中收集到的各种数据来验证几个假设,包括:(1)物种之间的化学差异与环境参数和生境和微生境的结构复杂性相关;(2)、在存在或不存在表皮腺体和化学信号的情况下,蜥蜴生命树的主要转变在栖息地/微栖息地中发生了变化(如温度,湿度和太阳辐射偏好的变化);(3)整个蜥蜴生命树的表皮腺体的独立起源具有共同的遗传起源,为这些结构具有深层和共同的祖先提供了强有力的证据。通过使用蜥蜴表皮腺体作为我们的研究系统,该项目将提供对新奇的演变以及在交流和行为中发挥重要作用的结构的深入了解。该奖项反映了NSF的法定使命,并通过使用基金会的智力价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A novel epidermal gland type in lizards (α-gland): structural organization, histochemistry, protein profile and phylogenetic origins
蜥蜴的一种新型表皮腺体(α腺体):结构组织、组织化学、蛋白质谱和系统发育起源
  • DOI:
    10.1093/zoolinnean/zlaa140
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    2.8
  • 作者:
    Carvalho, André L;Jeckel, Adriana M;Nisa, Carolina;Luna, María Celeste;Piantoni, Carla
  • 通讯作者:
    Piantoni, Carla
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Adam Leache其他文献

Adam Leache的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Adam Leache', 18)}}的其他基金

Collaborative Research: Species delimitation in North American lizards
合作研究:北美蜥蜴的物种界定
  • 批准号:
    2023723
  • 财政年份:
    2020
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Integrating Physiology and Genomics to Test for Local Adaptation in a Montane Ectotherm
论文研究:整合生理学和基因组学来测试山地变温动物的局部适应
  • 批准号:
    1701231
  • 财政年份:
    2017
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Investigating the Joint Effects of Phylogeny and Adaptation on Phenotypic Variation at a Continental Scale (Serpentes:Thamnophis)
论文研究:研究系统发育和适应对大陆尺度表型变异的联合影响(蛇类:Thamnophis)
  • 批准号:
    1600884
  • 财政年份:
    2016
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Hybrid zone formation and comparative genomic divergences in South American lizards (Iguania: Liolaemidae)
论文研究:南美蜥蜴(鬣蜥:Liolaemidae)的杂交区形成和比较基因组差异
  • 批准号:
    1500933
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Investigating the genomic structure of speciation: a comparative approach using wagtails (Aves: Motacilla)
论文研究:研究物种形成的基因组结构:使用鹡鸰的比较方法(Aves:Motacilla)
  • 批准号:
    1501131
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
COLLABORATIVE RESEARCH: Mechanisms of Diversification in West African Rainforest Amphibians and Reptiles
合作研究:西非雨林两栖动物和爬行动物的多样化机制
  • 批准号:
    1456098
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Comparative Phylogeography and Thermal Ecology of Puerto Rican Anoles
论文研究:波多黎各安乐蜥的比较系统发育地理学和热生态学
  • 批准号:
    1501134
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
Resolving rapid radiations and recent speciation in North American spiny lizards (Sceloporus)
解决北美刺蜥蜴(Sceloporus)的快速辐射和近期物种形成问题
  • 批准号:
    1144630
  • 财政年份:
    2012
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Continuing Grant
NSF Postdoctoral Research Fellowship in Biology for FY 2008
2008 财年 NSF 生物学博士后研究奖学金
  • 批准号:
    0805455
  • 财政年份:
    2008
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Fellowship

相似国自然基金

Research on Quantum Field Theory without a Lagrangian Description
  • 批准号:
    24ZR1403900
  • 批准年份:
    2024
  • 资助金额:
    0.0 万元
  • 项目类别:
    省市级项目
Cell Research
  • 批准号:
    31224802
  • 批准年份:
    2012
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Cell Research
  • 批准号:
    31024804
  • 批准年份:
    2010
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Cell Research (细胞研究)
  • 批准号:
    30824808
  • 批准年份:
    2008
  • 资助金额:
    24.0 万元
  • 项目类别:
    专项基金项目
Research on the Rapid Growth Mechanism of KDP Crystal
  • 批准号:
    10774081
  • 批准年份:
    2007
  • 资助金额:
    45.0 万元
  • 项目类别:
    面上项目

相似海外基金

Research on EBI3-containing cytokines produced by epidermal keratinocytes in psoriatic lesions
银屑病皮损表皮角质形成细胞产生的含EBI3细胞因子的研究
  • 批准号:
    20K08672
  • 财政年份:
    2020
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Collaborative Research: Epidermal gland evolution and the origins of structural and chemical signaling diversity
合作研究:表皮腺进化以及结构和化学信号多样性的起源
  • 批准号:
    1855875
  • 财政年份:
    2019
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Continuing Grant
Collaborative Research: An Integrated Experimental and Computational Approach to Discover Biomechanical Mechanisms of Leaf Epidermal Morphogenesis
合作研究:探索叶表皮形态发生生物力学机制的综合实验和计算方法
  • 批准号:
    1715544
  • 财政年份:
    2017
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
Collaborative Research: An Integrated Experimental and Computational Approach to Discover Biomechanical Mechanisms of Leaf Epidermal Morphogenesis
合作研究:探索叶表皮形态发生生物力学机制的综合实验和计算方法
  • 批准号:
    1715444
  • 财政年份:
    2017
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
SCH: INT: Collaborative Research: Replicating Clinic Physical Therapy at Home: Touch, Depth, and Epidermal Electronics in an Interactive Avatar System
SCH:INT:合作研究:在家复制临床物理治疗:交互式化身系统中的触摸、深度和表皮电子
  • 批准号:
    1521532
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
SCH: INT: Collaborative Research: Replicating Clinic Physical Therapy at Home: Touch, Depth, and Epidermal Electronics in an Interactive Avatar System
SCH:INT:合作研究:在家复制临床物理治疗:交互式化身系统中的触摸、深度和表皮电子
  • 批准号:
    1522125
  • 财政年份:
    2015
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Standard Grant
Research on Epidermal Cell Differentiation Inhibitor EDIN producing Staphylococcus aureus
金黄色葡萄球菌产生表皮细胞分化抑制剂EDIN的研究
  • 批准号:
    22790408
  • 财政年份:
    2010
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Pioneering Research to Elucidate the Pathogenic Mechanism and Genetic Susceptibility of Stevens Johnson Syndrome/Toxic Epidermal Necrolysis
阐明史蒂文斯约翰逊综合征/中毒性表皮坏死松解症致病机制和遗传易感性的开创性研究
  • 批准号:
    22390325
  • 财政年份:
    2010
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Research of new recombinant anticancer drug against epidermal growth factor receptor as a molecular target
以表皮生长因子受体为分子靶点的新型重组抗癌药物研究
  • 批准号:
    13671338
  • 财政年份:
    2001
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
RESEARCH FOR TRANSMEMBRANE SIGNALING SYSTEM OF EPIDERMAL KERATINOCYTES ; INTRACELLULAR FREE CALCIUM AND PROTEIN KINASE C.
表皮角质细胞跨膜信号系统研究;
  • 批准号:
    05670717
  • 财政年份:
    1993
  • 资助金额:
    $ 48.88万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了