Collaborative Research: Epidermal gland evolution and the origins of structural and chemical signaling diversity

合作研究：表皮腺进化以及结构和化学信号多样性的起源

• 批准号: 1855845
• 负责人: Adam Leache
• 金额: $ 48.88万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-12-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1855845&HistoricalAwards=false
• 关键词: Collaborative; Research; Epidermal; gland; evolution

Animal communication systems have evolved an extraordinarily varied set of morphological and physiological structures and signals in order to control essential behavioral interactions, such as individual recognition, establishment of social hierarchies, territoriality, and intersexual selection. Visual, acoustic, and chemical signaling modes allow for complex repertoires of behavioral displays, yet little is known of how communication systems originated and evolved in most species in the animal tree of life, including reptiles. This project aims to fill this important gap by investigating the origin and evolution of novel communication mechanisms (epidermal glands) in lizards and how such systems are shaped by ecological and environmental parameters. Results from this research will provide a framework for predicting how human-induced environmental changes could impact chemical signaling. This project converges with NSF priorities for both science and society by expanding natural history collections and genetic resources in the U.S., building large data sets for comparative studies, developing new teaching materials focused on chemical communication, and directly contributing to scientific education and public outreach with the development of a new public exhibit at the Burke Museum of Natural History and Culture.Among lizards and snakes, chemical signaling has been increasingly acknowledged as a critical, yet underappreciated, component of communication. This project will use integrative methods and tools, including advanced imaging, biochemistry, phylogenetics, and gene expression across diverse lizard groups from North America, South America, and Africa to investigate the evolution of novel epidermal glands that are crucial in mediating behavioral interactions on several groups of lizards. This project will test several hypotheses with the diverse datatypes collected over the course of the research, including (1) chemical differences between species correlate with environmental parameters and structural complexity of the habitats and microhabitats; (2), major transitions in the presence or absence of epidermal glands and chemical signals across the lizard tree of life track shifts in habitat/microhabitat (such as changes in temperature, humidity, and solar radiation preferences); (3) independent origins of epidermal glands across the lizard tree of life share a common genetic origin, providing strong evidence that such structures share deep and common ancestry. By using lizard epidermal glands as our study system, this project will provide insight into the evolution of novelty and those structures that play important roles in communication and behavior.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

动物通信系统已经进化出一套非常不同的形态和生理结构和信号，以控制基本的行为相互作用，如个体识别、社会等级的建立、领地和两性选择。视觉、声音和化学信号模式允许复杂的行为显示，但人们对通信系统如何在包括爬行动物在内的大多数动物生命树中起源和进化知之甚少。该项目旨在通过研究蜥蜴新的通讯机制(表皮腺体)的起源和进化，以及这种系统是如何受到生态和环境参数的影响来填补这一重要空白的。这项研究的结果将为预测人类引起的环境变化如何影响化学信号提供一个框架。这个项目与NSF在科学和社会方面的优先事项一致，通过扩大美国的自然历史收藏和遗传资源，为比较研究建立大型数据集，开发专注于化学交流的新教材，并通过在伯克自然历史和文化博物馆开发新的公共展览，直接为科学教育和公共宣传做出贡献。在蜥蜴和蛇中，化学信号越来越被认为是交流的关键组成部分，但却没有得到足够的重视。该项目将使用综合的方法和工具，包括先进的成像、生物化学、系统发育和来自北美、南美和非洲的不同蜥蜴群体的基因表达，来研究新的表皮腺的进化，这种腺体在调节几种蜥蜴群体的行为相互作用中至关重要。这个项目将用在研究过程中收集的不同数据类型来检验几个假说，包括：(1)物种之间的化学差异与环境参数和生境和微生境的结构复杂性相关；(2)存在或不存在表皮腺的重大转变以及生活在蜥蜴树上的化学信号在栖息地/微生境的变化(如温度、湿度和太阳辐射偏好的变化)；(3)蜥蜴生命树上表皮腺体的独立起源共享共同的遗传起源，提供了强有力的证据，表明这种结构具有深刻的共同祖先。通过使用蜥蜴表皮腺作为我们的研究系统，该项目将提供对新颖性的演变以及那些在沟通和行为中发挥重要作用的结构的洞察。该奖项反映了NSF的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

A novel epidermal gland type in lizards (α-gland): structural organization, histochemistry, protein profile and phylogenetic origins

蜥蜴的一种新型表皮腺体（α腺体）：结构组织、组织化学、蛋白质谱和系统发育起源

• DOI: 10.1093/zoolinnean/zlaa140
• 发表时间: 2020
• 期刊: Zoological Journal of the Linnean Society
• 影响因子: 2.8
• 作者: Carvalho, André L;Jeckel, Adriana M;Nisa, Carolina;Luna, María Celeste;Piantoni, Carla
• 通讯作者: Piantoni, Carla