Collaborative Research: Supramolecular Bio-nano-architectures as Biosensing Platforms

合作研究：超分子生物纳米结构作为生物传感平台

• 批准号: 1158943
• 负责人: Shelley Minteer
• 金额: $ 19.93万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1158943&HistoricalAwards=false
• 关键词: Collaborative; Research; Supramolecular; Bio; nano

1158936/1158943Atanassov/MinteerThe goal of this Collaborative Project is the development of self-powered enzymatic biosensors using direct electron transfer between novel enzymes and novel nano-structured electrode materials. The self-powering is achieved by means of constructing a fuel cell with enzyme-catalyzed electrodes that generates response to the environmental change without the need of an external power source. The research plan is focused on improving selectivity and sensitivity of sensors utilizing inhibition and activation-based self-powered sensing. This is a multidisciplinary research project between University of Utah and University of New Mexico who will be working together in order to understand and develop the materials systems needed for self powered biosensors/biofuel cells. The two universities will utilize this interest to train high school students, undergraduate students, and graduate students in the interdisciplinary sciences of bio-electrochemistry, bio-nanotechnology, biosensing and bio-inspired energy conversion. The immediate involvement of students from underrepresented minorities is expected and will be aggressively sought.

1158936/1158943Atanassov/Minteer 该合作项目的目标是利用新型酶和新型纳米结构电极材料之间的直接电子转移来开发自供电酶生物传感器。 自供电是通过构建带有酶催化电极的燃料电池来实现的，该燃料电池无需外部电源即可对环境变化产生响应。该研究计划的重点是利用基于抑制和激活的自供电传感来提高传感器的选择性和灵敏度。这是犹他大学和新墨西哥大学之间的一个多学科研究项目，双方将共同努力了解和开发自供电生物传感器/生物燃料电池所需的材料系统。两所大学将利用这一兴趣来培养生物电化学、生物纳米技术、生物传感和仿生能量转换等跨学科科学的高中生、本科生和研究生。预计并将积极寻求来自代表性不足的少数族裔的学生的立即参与。