FSML: Acquisition of a next generation high throughput DNA sequencer (Ion Torrent) for the Skidaway Institute of Oceanography

FSML：为斯基德威海洋研究所购买下一代高通量 DNA 测序仪 (Ion Torrent)

• 批准号: 1226686
• 负责人: Marc Frischer
• 金额: $ 11.87万
• 依托单位: University of Georgia Research Foundation Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1226686&HistoricalAwards=false
• 关键词: FSML; Acquisition; next; generation; throughput

The Skidaway Institute of Oceanography is awarded a grant to purchase high-throughput genome-sequencing equipment to provide a critical improvement in the infrastructure required to conduct nucleic-acid-based research at the Skidaway Institute of Oceanography. This next-generation DNA sequencing platform represents a quantum leap in DNA sequencing technology, bringing true high throughput DNA sequencing capacity within the reach of the field and marine lab research community. Massively parallel high throughput DNA sequencing is a core technology enabling global genetic analyses including whole genome sequencing and transcriptomics, which have transformed research in a wide array of fields, including in the Ocean Sciences. Research activities at the Skidaway Institute of Oceanography have increasingly utilized DNA and RNA sequence data with DNA sequencing required by at least 20 funded and several pending projects. Approximately 1/3 of the Skidaway Institute faculty (6 of 16) and several local, national and international collaborators routinely utilize sequencing technology as part of their research programs. Sequencing technology is being used to push the frontiers of many fields, but especially in biological and chemical oceanography where microorganisms dominate the biogeochemical cycling of critical nutrients and other elements. This technology is critical for elucidating new perspectives on the structure of food webs and parasitic and disease processes.This improvement will allow researchers to exponentially increase the amount of sequencing that can be generated for the same research funds. As a result, experiments requiring high throughput sequencing will become feasible in smaller projects, including student research activities. Acquisition of this capacity will enhance several educational opportunities through ongoing programs with other institutions, including the Historically Black Colleges and Universities Savannah State and Clark Atlanta. Skidaway faculty, staff and students also work with local K-12 educational systems to provide both pre- and in-service teachers with research experiences. Collaborations with partners on the Skidaway campus including the University of Georgia's Marine Education Center and Aquarium, Georgia Institute of Technology's Chemical Ecology Laboratory, Georgia Southern University's Applied Coastal Research Laboratory, The Georgia Department of Natural Resources Underwater Archaeology Field Station, The Nature Conservancy and NOAA Gray's Reef National Marine Sanctuary, also provide outlets for outreach and joint research. For more information about the Skidaway Institute of Oceanography please see its website at: http://www.skio.usg.edu/.

斯基德韦海洋学研究所获得一笔赠款，用于购买高通量基因组测序设备，以便对斯基德韦海洋学研究所进行核酸研究所需的基础设施进行重大改进。这款新一代DNA测序平台代表了DNA测序技术的一次飞跃，为现场和海洋实验室研究界带来了真正的高通量DNA测序能力。大规模并行高通量DNA测序是实现全球遗传分析的核心技术，包括全基因组测序和转录组学，这已经改变了包括海洋科学在内的广泛领域的研究。斯基达韦海洋学研究所的研究活动越来越多地利用DNA和RNA序列数据，至少有20个已获资助的项目和几个待决项目需要DNA测序。大约1/3的Skidaway研究所教师（16人中的6人）和一些地方，国家和国际合作者经常利用测序技术作为其研究计划的一部分。测序技术正被用于推动许多领域的前沿，特别是在生物和化学海洋学中，微生物主导着关键营养物质和其他元素的生物地球化学循环。 这项技术对于阐明食物网结构以及寄生虫和疾病过程的新观点至关重要。这一改进将使研究人员能够以指数方式增加相同研究资金所能产生的测序数量。因此，需要高通量测序的实验将在较小的项目中变得可行，包括学生的研究活动。获得这种能力将通过与其他机构，包括历史上的黑人学院和大学萨凡纳州和克拉克亚特兰大正在进行的方案，增加几个教育机会。Skidaway的教职员工和学生还与当地的K-12教育系统合作，为职前和在职教师提供研究经验。与斯基德韦校园的合作伙伴，包括格鲁吉亚大学的海洋教育中心和水族馆，格鲁吉亚理工学院的化学生态学实验室，格鲁吉亚南方大学的应用海岸研究实验室，格鲁吉亚自然资源部水下考古野外工作站，大自然保护协会和NOAA格雷礁国家海洋保护区的合作，也提供了外展和联合研究的渠道。欲了解更多关于Skidaway海洋学研究所的信息，请访问其网站：http://www.skio.usg.edu/。