MRI: Acquisition of a Hybrid Mass Spectrometry System for the Next Generation of Multidisciplinary Geosciences Research, Student Education and Training

MRI：采购混合质谱系统用于下一代多学科地球科学研究、学生教育和培训

• 批准号: 1229197
• 负责人: Rodger Harvey
• 金额: $ 51.76万
• 依托单位: Old Dominion University Research Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-10-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1229197&HistoricalAwards=false
• 关键词: MRI; Acquisition; Hybrid; Mass; Spectrometry

The PI's request funding to acquire a state-of-the-art, high-resolution, hybrid mass spectrometry system and associated peripherals (LC-MSn). The proposed instrumentation represents a strategic expansion of ODU research capabilities in marine ecosystem studies and will provide new critical research tools for a team of faculty, researchers and students. The LC-MSn instrumentation will be used for structural characterization and quantitative analysis of a diverse suite of polar molecules, most of which are biotic in origin and represent living materials and metabolites, including those of emerging environmental and ecological health concerns. A range of interdisciplinary research activities will benefit from the proposed instrumentation, include: elucidating biogeochemical cycling of organic matter in the Arctic Ocean by analysis of molecular organic markers; utilizing environmental proteomics to understand marine nitrogen cycling and geochemical processes; analyzing transformations of organic nitrogen in coastal systems; characterizing organic molecules associated with marine protists; and addressing the roles of dissolved organic ligands in the sorption and bioavailability of trace metals. This new instrumentation will facilitate further development of ongoing and future research projects that require new levels of analytical sophistication for characterization of organic compounds present in marine and estuarine ecosystems and their environmental context. Broader Impacts: The requested instrumentation will help the continued development of infrastructure for research. Graduate students as well as undergraduate students will benefit from this state-of-the-art facility. ODU has an outreach program through the Virginia Aquarium and Marine Science Center which provides excellent opportunities for public outreach. The research derived from the use of the instrument is to be highlighted through the aquarium and public lectures.

PI要求提供资金以获得最先进的高分辨率混合质谱系统和相关外围设备（LC-MSn）。拟议的仪器代表了ODU在海洋生态系统研究中的研究能力的战略扩展，并将为教师，研究人员和学生团队提供新的关键研究工具。LC-MSn仪器将用于对一系列极性分子进行结构表征和定量分析，其中大多数分子是生物来源的，代表了生命物质和代谢物，包括新出现的环境和生态健康问题。一系列跨学科研究活动将受益于拟议的仪器，包括：通过分析分子有机标记物阐明北冰洋有机物的生物地球化学循环;利用环境蛋白质组学了解海洋氮循环和地球化学过程;分析沿海系统中有机氮的转化;确定与海洋原生生物有关的有机分子的特征;以及解决溶解的有机配体在痕量金属的吸附和生物利用度中的作用。这种新的仪器将促进正在进行的和未来的研究项目的进一步发展，需要新的水平的分析复杂的表征存在于海洋和河口生态系统及其环境背景下的有机化合物。更广泛的影响：所要求的仪器将有助于继续发展研究基础设施。研究生以及本科生将受益于这个国家的最先进的设施。ODU通过弗吉尼亚水族馆和海洋科学中心开展了一项外联方案，为公众外联提供了极好的机会。通过水族馆和公开讲座，将突出使用该仪器进行的研究。