MRI: Development of nano-CT-based elastography system for three-dimensional deformation field and elastic characterization of heterogeneous materials

这一重大研究仪器(MRI)奖支持基于纳米CT的弹性成像系统的开发，该系统将允许以亚微米分辨率对深度嵌入的变形场的局部细节进行三维(3-D)重建，并对图像进行相关表征，以生成各向异性弹性图。通过集成纳米CT自适应压缩波发生器，该系统可以揭示材料内部局部变形和力学分布的大量隐藏信息。纳米CT提供的毫米级穿透长度和亚微米分辨率的独特组合使其成为非侵入性三维机械变形成像的理想工具。如果成功，弹性成像系统的开发将增强微/纳米系统开发和材料表征的整体能力。此外，拟议的发展将在加州大学欧文分校的所有五个工程系开展令人兴奋的本科生和研究生教育活动。该项目的跨学科性质也将有助于吸引和留住来自代表性不足群体的学生，并使他们接触到最先进的研究。该项目将通过提交出版物、在会议上作陈述以及通过互联网发布非技术性出版物来广泛传播其调查结果。

This Major Research Instrumentation (MRI) award supports the development of a nano-CT-based elastography system that will permit three-dimensional (3-D) reconstruction of deeply embedded local details of a deformation field with sub-micron resolution and the associated characterization of images to generate anisotropic modulus elastograms. With the integration of a nano-CT adaptive compression wave generator, the system can unveil a significant amount of hidden information regarding the localized deformation and mechanical distribution within materials. The unique combination of milimeter-scale penetration length with sub-micron resolution offered by nano-CT makes it an ideal tool for noninvasive 3-D mechanical deformation imaging. If successful, the development for the elastography system will enhance the overall capabilities for micro-/nano-systems development and materials characterization. Furthermore, the proposed development will enable exciting educational activities both at the undergraduate and graduate level, in all five engineering departments at UC Irvine. This interdisciplinary nature of the project will also help attract and retain students from underrepresented groups and expose them to the state-of-the-art research. The project will disseminate its findings broadly through submission of publications, presentations in conferences, and non-technical publications through the internet.