MRI: Development of nano-CT-based elastography system for three-dimensional deformation field and elastic characterization of heterogeneous materials

MRI：开发基于纳米CT的弹性成像系统，用于三维变形场和异质材料的弹性表征

• 批准号: 1229405
• 负责人: Lizhi Sun
• 金额: $ 55.55万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2016-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1229405&HistoricalAwards=false
• 关键词: MRI; Development; nano; CT; based

This Major Research Instrumentation (MRI) award supports the development of a nano-CT-based elastography system that will permit three-dimensional (3-D) reconstruction of deeply embedded local details of a deformation field with sub-micron resolution and the associated characterization of images to generate anisotropic modulus elastograms. With the integration of a nano-CT adaptive compression wave generator, the system can unveil a significant amount of hidden information regarding the localized deformation and mechanical distribution within materials. The unique combination of milimeter-scale penetration length with sub-micron resolution offered by nano-CT makes it an ideal tool for noninvasive 3-D mechanical deformation imaging. If successful, the development for the elastography system will enhance the overall capabilities for micro-/nano-systems development and materials characterization. Furthermore, the proposed development will enable exciting educational activities both at the undergraduate and graduate level, in all five engineering departments at UC Irvine. This interdisciplinary nature of the project will also help attract and retain students from underrepresented groups and expose them to the state-of-the-art research. The project will disseminate its findings broadly through submission of publications, presentations in conferences, and non-technical publications through the internet.

该主要研究仪器（MRI）奖支持基于纳米CT的弹性成像系统的开发，该系统将允许三维（3-D）重建具有亚微米分辨率的变形场的深嵌入局部细节以及图像的相关表征，以生成各向异性模量弹性图。通过集成nano-CT自适应压缩波发生器，该系统可以揭示大量关于材料内局部变形和机械分布的隐藏信息。纳米CT提供的毫米级穿透长度与亚微米分辨率的独特组合使其成为非侵入性3-D机械变形成像的理想工具。如果成功，弹性成像系统的开发将提高微/纳米系统开发和材料表征的整体能力。此外，拟议的发展将使令人兴奋的教育活动，无论是在本科和研究生水平，在所有五个工程部门在加州大学欧文分校。该项目的跨学科性质也将有助于吸引和留住来自代表性不足群体的学生，并使他们接触最先进的研究。该项目将通过提交出版物、在会议上发言和通过互联网发表非技术性出版物，广泛传播其研究结果。