Travel Award for Workshop "Towards in Silico Biological Cells: Bridging Experiments and Simulations" Lausanne, Switzerland

瑞士洛桑“迈向硅生物细胞：桥接实验与模拟”研讨会旅行奖

• 批准号: 1243438
• 负责人: Zaida Luthey-Schulten
• 金额: $ 0.66万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2013-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1243438&HistoricalAwards=false
• 关键词: Travel; Award; Workshop; Towards; Silico

The July 9-12, 2012 workshop "Towards in silico biological cells: Bridging experiments and simulations" in Lausanne, Switzerland will bring together researchers from two basic and complementary approaches for simulating the dynamics of cellular processes within the cytoplasm of bacterial cells: particle-based Brownian dynamics algorithms that have been used to describe the diffusive transport in crowded environments and reaction-diffusion master equations that have been used to describe stochastic kinetics of gene expression, genetic switches and biochemical pathways functioning in modeled biological cells. This Workshop will provide the opportunity to bring researchers from the scientific fields of molecular simulations and system biology together with experimentalists who are labeling and imaging cellular components. We envision that this cross fertilization will lead to significant scientific advances in the computational modeling of an entire cell, its components, cell division and the coupling of universal processes of transcription and translation to the response of the cell's metabolic network.

2012年7月9日至12日在瑞士洛桑举行的研讨会“Towards in silico biological cells：Bridging experiments and simulations”将汇集来自两种基本和互补方法的研究人员，用于模拟细菌细胞质内细胞过程的动态：基于粒子的布朗动力学算法，已被用来描述在拥挤的环境和反应扩散运输-扩散主方程已被用来描述随机动力学的基因表达，遗传开关和生化途径中发挥作用的模拟生物细胞。本次研讨会将提供机会，使来自分子模拟和系统生物学科学领域的研究人员与正在标记和成像细胞成分的实验人员一起。我们设想，这种交叉受精将导致整个细胞的计算建模，其组件，细胞分裂和耦合的通用过程的转录和翻译细胞的代谢网络的响应显着的科学进步。