Femtosecond Stimulated Raman Scattering, Time Resolved Dynamics, and Electron-Nuclear coupling in Biomolecules

在这项由化学系化学结构、动力学和机制计划(A)、分子和细胞生物科学系分子生物物理计划和物理系生命系统物理学计划资助的奖项中，东北大学的Paul M.Champion教授将使用现代超快激光方法研究生物分子系统利用热能进行和控制生化反应的方法。特别是，Champion教授和他的研究小组将使用振动相干光谱(VCS)和飞秒受激拉曼散射(FSRs)来探索复杂生物分子的低频振动如何影响或修饰大生物分子的反应性。了解生物分子体系的化学反应性对于理解生物系统在宏观尺度上的运行方式至关重要。这一领域的进步将带来医学和生物技术的进步。与冠军教授合作的本科生和研究生将在生物学和物理科学的交叉点接受尖端科学方面的出色培训。钱皮恩教授还积极与东北地区和波多黎各代表不足的群体的科学家合作。

In this award, funded by the Chemical Structure, Dynamics, and Mechanisms Program (A) of the Division of Chemistry, the Molecular Biophysics Program of the Division of Molecular and Cellular Biosciences, and the Physics of Living Systems Program of the Division of Physics, Prof. Paul M. Champion at Northeastern University will use modern, ultrafast laser methods to study the ways in which biomolecular systems use thermal energy to carry out and control biochemical reactions. In particular, Prof. Champion and his research group will use vibrational coherence spectroscopy (VCS) and femtosecond stimulated Raman scattering (FSRS) will be used to probe the ways in which low-frequency vibrations of complex biomolecules influence or modify the reactivity of large biomolecules.Understanding the chemical reactivity of biomolecular systems is critical towards understanding the way that biological systems operate at the macroscopic scale. Advances in this field will yield advances in medicine and biotechnology. The undergraduate and graduate students working with Prof. Champion will receive excellent training in cutting-edge science at the intersection of Biology and the Physical Sciences. Prof. Champion is also actively collaborating with scientists from underrepresented groups at Northeastern as well as in Puerto Rico.