Differentiation of Cord Blood Stem cells into Thymus (T) cells with regulatory phenotype and function
脐带血干细胞分化为具有调节表型和功能的胸腺 (T) 细胞
基本信息
- 批准号:LP0989577
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Linkage Projects
- 财政年份:2009
- 资助国家:澳大利亚
- 起止时间:2009-01-01 至 2015-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This project will develop technologies for a stem cell therapy platform based on cord blood stem cells, to enable treatment of autoimmune diseases or transplants. Building on the University of Adelaide's frontier demonstration of differentiation of regulatory Thymus (T) cells from cord blood stem cells, the project will develop techniques to expand the numbers of T cells generated. This has the potential to maintain Australia's lead in differentiation of cord blood stem cells and to provide a significant breakthrough in potential treatments of autoimmune diseases (e.g. type 1 diabetes) or transplantation. These diseases affect both a healthy start to life and healthy ageing, and an Australian invention to treat or cure them would have global impact.
该项目将开发基于脐带血干细胞的干细胞治疗平台技术,以治疗自身免疫性疾病或移植。在阿德莱德大学的脐带血干细胞分化调节性T细胞的前沿示范的基础上,该项目将开发扩大产生的T细胞数量的技术。这有可能保持澳大利亚在脐带血干细胞分化方面的领先地位,并在自身免疫性疾病(例如1型糖尿病)或移植的潜在治疗方面取得重大突破。这些疾病既影响生命的健康开始,也影响健康的老龄化,澳大利亚治疗或治愈这些疾病的发明将产生全球影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Prof Simon Barry其他文献
Prof Simon Barry的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
相似国自然基金
基于tumor cord-PBPK偶联模型的抗肿瘤药物药动学预测研究
- 批准号:81703454
- 批准年份:2017
- 资助金额:20.1 万元
- 项目类别:青年科学基金项目
相似海外基金
Differentiation of Cord Blood Mesenchymal Stem Cells to Corneal Endothelium
脐带血间充质干细胞向角膜内皮的分化
- 批准号:
7570902 - 财政年份:2009
- 资助金额:
-- - 项目类别:
Differentiation of Cord Blood Mesenchymal Stem Cells to Corneal Endothelium
脐带血间充质干细胞向角膜内皮的分化
- 批准号:
7844831 - 财政年份:2009
- 资助金额:
-- - 项目类别:
Pancreatic Differentiation of Cord Blood Stem Cells using Smart Surfaces
使用智能表面对脐带血干细胞进行胰腺分化
- 批准号:
LP0776600 - 财政年份:2008
- 资助金额:
-- - 项目类别:
Linkage Projects
In vitro Germ Cell Differentiation of Cord-Blood-derived Unrestricted Somatic Stem Cells (USSC)
脐带血来源的非限制性成体干细胞 (USSC) 的体外生殖细胞分化
- 批准号:
55928383 - 财政年份:2007
- 资助金额:
-- - 项目类别:
Research Units
Study on hepatic differentiation of mesenchymal stem cells derived from human umbilical cord blood, and cell therapy for liver disease by use of mesenchymal stem cells.
人脐带血间充质干细胞向肝脏分化的研究,以及利用间充质干细胞治疗肝病的细胞疗法。
- 批准号:
17590625 - 财政年份:2005
- 资助金额:
-- - 项目类别:
Grant-in-Aid for Scientific Research (C)
The establishment of methods for cardiomyocyte differentiation with human umbilical cord blood-derived mesenchymal stem cells aimed the application into the treatment of pediatric heart failures
建立人脐带血间充质干细胞分化心肌细胞的方法,旨在应用于小儿心力衰竭的治疗
- 批准号:
16390399 - 财政年份:2004
- 资助金额:
-- - 项目类别:
Grant-in-Aid for Scientific Research (B)
IN VITRO DIFFERENTIATION OF CORD BLOOD STEM CELLS INTO ENDOCRINE PANCREAS FOR I
脐带血干细胞体外分化为内分泌胰腺
- 批准号:
7202933 - 财政年份:2004
- 资助金额:
-- - 项目类别:
In vivo differentiation and proliferation of mesenchymal stem cells derived from cord blood stem cell transplantation donor.
来自脐带血干细胞移植供体的间充质干细胞的体内分化和增殖。
- 批准号:
15591102 - 财政年份:2003
- 资助金额:
-- - 项目类别:
Grant-in-Aid for Scientific Research (C)
Differentiation-induction of antibody producing human B cells from cord blood CD34+ cells in mice for generating monoclonal antibody used in clinical therapy
从小鼠脐带血 CD34 细胞中分化诱导产生抗体的人 B 细胞,以产生用于临床治疗的单克隆抗体
- 批准号:
12557032 - 财政年份:2000
- 资助金额:
-- - 项目类别:
Grant-in-Aid for Scientific Research (B)
Differentiation of potential of umbilical cord blood cells into cartilage and ligament cells.
脐带血细胞分化为软骨和韧带细胞的潜力。
- 批准号:
12671433 - 财政年份:2000
- 资助金额:
-- - 项目类别:
Grant-in-Aid for Scientific Research (C)