MRI: Acquisition of an Automated Single-Crystal X-Ray Diffractometer for Research and Teaching

MRI：购买自动单晶 X 射线衍射仪用于研究和教学

• 批准号: 1336071
• 负责人: Kung Wang
• 金额: $ 21.7万
• 依托单位: West Virginia University Research Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-15 至 2016-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1336071&HistoricalAwards=false
• 关键词: MRI; Acquisition; Automated; Single; Crystal

With this award from the Major Research Instrumentation Program that is co-funded by the Chemistry Research Instrumentation and Facilities (CRIF) Program, Professor Kung Wang from West Virginia University and colleagues Jeffrey Petersen, Xiaodong Shi, Jessica Hoover and Brian Popp will acquire a single crystal X-ray diffractometer that will replace an obsolete diffractometer with a single-point detector. The project is aimed at enhancing research and education at all levels, especially in areas such as (a) studies of transition metal complexes for promoting catalytic C-C bond forming and dehydrogenative cross coupling reactions, for modeling enzymatic systems capable of the reductive coupling of CO, or for developing new achiral and chiral reagents; (b) preparation of ambiphilic, BINOLate-type, and 1,2,3-triazole ligand systems (BINOL = the chiral 1,1'-binaphthyl-2,2'-diol); and (c) synthesis of highly strained polycyclic aromatics that serve as end-cap templates for carbon nanotubes and heteroaromatics that display biological activity.An X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here will impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research and research training. It will be the only modern diffractometer in the state which will positively benefit society through research, education, workforce training and outreach and increase the already historic collaborations with outer-of-state schools and used for summer enrichment programs involving middle, high-school and undergraduate as well as graduate students in the area.

在化学研究仪器和设施(CRIF)计划共同资助的重大研究仪器计划的这一奖项下，西弗吉尼亚大学的王功教授及其同事Jeffrey Petersen、施晓东、Jessica Hoover和Brian Popp将获得一台单晶X射线衍射仪，该衍射仪将用单点探测器取代过时的衍射仪。该项目旨在加强各级的研究和教育，特别是在以下领域：(A)过渡金属络合物用于促进催化C-C键形成和脱氢交叉偶联反应的研究，用于模拟能够使CO还原偶联的酶体系，或用于开发新的非手性和手性试剂；(B)双亲性、联苯醇型和1，2，3-三氮唑配体体系的制备(BINOL=手性1，1‘-联萘-2，2’-二醇)；和(C)合成高应变多环芳烃，作为碳纳米管的端盖模板和显示生物活性的杂芳烃。X射线衍射仪可以准确和精确地测量分子的全部三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这里描述的研究将影响许多领域，包括有机化学和无机化学、材料化学和生物化学。该仪器将成为教学以及研究和研究培训的组成部分。它将是该州唯一一台将通过研究、教育、劳动力培训和推广积极造福社会的现代衍射仪，并将增加与州外学校已经具有历史意义的合作，并用于该地区初中、高中和本科生以及研究生的夏季丰富项目。