International Advanced Course on Regenerative Medicine Manufacturing Workshop to be held on April 28-May 3, 2013 in Algarve, Portugal

干细胞工程是一个快速发展的跨学科领域，它将干细胞生物学原理与物理科学和工程学相结合，以推进再生细胞治疗和体外诊断平台，使其具有商业可行性和可扩展性，这将对生物医学科学和整个社会产生重大影响。虽然干细胞研究即将对医学领域的许多方面产生广泛影响，如再生医学、药物发现和开发、基于细胞的诊断和癌症，但为这些诊断和治疗应用制造足够数量的功能性干细胞所需的生物过程工程仍处于早期发展阶段。干细胞研究领域的现状为科学家和工程师提供了一个独特的机会，他们共同努力，为干细胞的表型表征、繁殖、分化和生物加工提供了强大的、可重复的和可扩展的方法。干细胞研究带来的许多独特挑战可以通过应用相邻学科的创新技术进步来解决，这些学科的目的相似，但应用不同。研讨会期间的演讲将包括干细胞生物学的基础知识、可扩展培养技术、生物分析表征、制造实践和使能技术。该计划为学员和研究人员提供了一个独特的机会，以可扩展的方式学习干细胞分离，表征，繁殖和分化的常见和定量方法，以有效地产生足够数量的干细胞和衍生物，以可访问的格式，以便产生一系列新的干细胞治疗和诊断应用。学术价值：本次研讨会的学术价值在于激发创造性、原创性和潜在变革性的新想法和概念，并确定再生医学制造的未来方向，从而对干细胞生物学、工程、制造和医学领域产生更广泛的影响。更广泛的影响：本次研讨会的讨论将促进我们对进一步发展再生医学生物制造的潜在科学和技术问题和挑战的理解，并促进可能导致新的全球合作和倡议的跨学科互动。通过让女性和少数民族参与者参加讲习班，将扩大代表性不足群体的参与。该研讨会还将促进转化研究和创新，促进教育和研究的整合，并激励和帮助培养干细胞工程和制造的年轻未来领导者。工作坊网站- http://berg.ist.utl.pt/regenerative-medicine/

CBET - 1338197PI: Todd McDevittStem cell engineering is a rapidly emerging interdisciplinary field that integrates principles of stem cell biology with the physical sciences and engineering to advance regenerative cell therapies and in vitro diagnostic platforms to commercially viable and scalable technologies that will significantly impact the biomedical sciences and society at large. While stem cell research is on the verge of broadly impacting many elements of the medical field regenerative medicine, drug discovery and development, cell-based diagnostics and cancer the bioprocess engineering that will be required to manufacture sufficient quantities of functional stem cells for these diagnostic and therapeutic applications is at an early stage of development. The current state of the field of stem cell research offers a unique opportunity for scientists and engineers, working together, to contribute significantly to the generation of robust, reproducible and scalable methods for phenotypic characterization, propagation, differentiation and bioprocessing of stem cells.Many of the unique challenges posed by stem cell research could be addressed by applying innovative technological advances occurring in adjacent disciplines for similar purposes, but different applications. Presentations during the workshop will include talks on fundamental basics of stem cell biology, scaleable culture techniques, bioanalytical characterization, manufacturing practices and enabling technologies. This program provides a unique opportunity for trainees and researchers to learn about common and quantitative methods for stem cell isolation, characterization, propagation and differentiation in a scalable manner to efficiently produce sufficient numbers of stem cells and derivatives in accessible formats in order to yield a spectrum of novel therapeutic and diagnostic applications of stem cells.Intellectual Merit:The intellectual merit of the proposed workshop is the stimulation of creative, original, and potentially transformative new ideas and concepts and the identification of future directions in regenerative medicine manufacturing, thus generating a broader impact to the fields of stem cell biology, engineering, manufacturing and medicine.Broader Impacts:The discussions at this workshop will advance our understanding of the underlying scientific and technological issues and challenges in further developing regenerative medicine biomanufacturing, and facilitate interdisciplinary interactions that may lead to new global collaborations and initiatives. By having female and minority participants attend the workshop, it will broaden the participation of underrepresented groups. This workshop will also stimulate translational research and innovation, facilitate the integration of education and research, and inspire and help train the young future leaders of stem cell engineering and manufacturing. Workshop Website - http://berg.ist.utl.pt/regenerative-medicine/