CSHL Advanced Bacterial Genetics Course

CSHL高级细菌遗传学课程

• 批准号: 1713681
• 负责人: Terri Grodzicker
• 金额: $ 45万
• 依托单位: Cold Spring Harbor Laboratory
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1713681&HistoricalAwards=false
• 关键词: CSHL; Advanced; Bacterial; Genetics; Course

Intellectual Merit: Cold Spring Harbor Laboratory's three-week summer course in Advanced Bacterial Genetics prepares students for modern scientific research in molecular genetics. Students gain hands-on training in the theoretical knowledge and practical skills needed to analyze and manipulate bacterial genes and genomes both in vivo and in vitro. The course provides training in classical bacterial genetics and also exposes the students to modern molecular technologies, including high-throughput approaches, methods for genome engineering, and production of large-scale data sets. In addition, the students receive bioinformatics training that is necessary for modern molecular genetics including PCR and oligonucleotide design and DNA sequence analysis including genome assembly and annotation. The course is taught by instructors, who are chosen based on their expertise and contributions to the field of bacterial genetics and molecular biology. The instructors invite guest lecturers to give up-to-the-minute reports on current research on diverse topics, while emphasizing the genetic methodologies they used to study these topics. The format, which includes lectures, laboratory work and many opportunities for informal discussions with instructors and students, fully immerses the students in laboratory-based coursework. Course participants are chosen from a pool of highly qualified applicants ranging from early career scientists to senior investigators and coming from diverse research backgrounds, including biology, chemistry, engineering, physics, and mathematics.Broader Impacts: The course provides a collaborative environment for intense training in modern microbial genetics. For students working in fields such as synthetic biology, biotechnology, systems biology, or modeling, the course provides them with a strong foundation to understand and apply genetic methodologies. It also provides microbiology students, working with a diverse array of microbes, with an understanding of how to develop genetic methods needed to study non-model microorganisms. The course trains an ethnically, racially and scientifically diverse group and stimulates interaction among all participants of the course and provides mentorship towards research in modern microbiology.

智力优势：冷泉港实验室为期三周的高级细菌遗传学暑期课程为学生在分子遗传学方面的现代科学研究做好准备。 学生获得在体内和体外分析和操纵细菌基因和基因组所需的理论知识和实践技能的实践培训。 该课程提供经典细菌遗传学的培训，并让学生接触现代分子技术，包括高通量方法、基因组工程方法和大规模数据集的产生。 此外，学生还将接受现代分子遗传学所必需的生物信息学培训，包括PCR和寡核苷酸设计以及DNA序列分析，包括基因组组装和注释。 该课程由教师授课，他们是根据他们的专业知识和对细菌遗传学和分子生物学领域的贡献而选择的。讲师邀请客座讲师就不同主题的当前研究给出最新的报告，同时强调他们用于研究这些主题的遗传方法。 该格式，其中包括讲座，实验室工作和许多机会与教师和学生进行非正式讨论，充分沉浸在基于实验室的课程的学生。 课程参与者是从高素质的申请者中挑选出来的，从早期的职业科学家到高级研究人员，来自不同的研究背景，包括生物学，化学，工程学，物理学和数学。更广泛的影响：该课程为现代微生物遗传学的强化培训提供了一个合作的环境。对于在合成生物学，生物技术，系统生物学或建模等领域工作的学生，本课程为他们提供了理解和应用遗传方法的坚实基础。它还为微生物学学生提供了与各种微生物一起工作的机会，了解如何开发研究非模型微生物所需的遗传方法。该课程培训了一个民族、种族和科学上多样化的群体，促进了课程所有参与者之间的互动，并为现代微生物学研究提供了指导。