IDBR: TYPE B: High temperature MEMS flow controller for MEMS enabled chopper-modulated gas chromatography - electroantennography (MEMS- GC-EAG) and other GC applications

IDBR：B 型：高温 MEMS 流量控制器，适用于 MEMS 斩波调制气相色谱 - 触角电图 (MEMS-GC-EAG) 和其他 GC 应用

• 批准号: 1353870
• 负责人: Siyang Zheng
• 金额: $ 44.33万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1353870&HistoricalAwards=false
• 关键词: IDBR; TYPE; temperature; MEMS; flow

An award is made to the Pennsylvania State University to develop a microfabricated high-temperature flow control device for gas chromatography (GC) applications that will benefit agriculture and forestry to better target invasive species and pests.Non Technical Abstract:The device will enable a technique named chopper-modulated electroantennograph (EAG), which uses GC to separate volatile odorants, and insect antennae as detectors to identify specific compounds that are of importance to, and able to be sensed by the insect. As a result of millions of years of evolution, insect antennae are capable of detecting certain chemicals more sensitively and specifically than artificial chemical sensors. The chopper-modulated GC-EAG method will use the proposed flow control device to regulate gas flow in GC and improve the signal-to-noise ratio of the EAG, with a resulting several orders of magnitude improvement in detection sensitivity for behaviorally important volatile chemicals. The use of the proposed device in other GC applications can potentially contribute to the general chemical sensing community and benefit the society with more sensitive analysis for environmental monitoring, food safety, disease diagnostics and etc. The education plan includes student training and curriculum development. The instrument will also be integrated into various outreach activities including the annual PSU "Great Insect Fair", at which attendance routinely surpasses 8,000 people annually.Technical Abstract:The overall goal of the research is to develop a high temperature microelectromechanical system (MEMS) flow controller (HT-MEMS flow controller) whose purpose is to operate inside a conventional gas chromatography (GC) oven to enable chopper-modulated electroantennograph (EAG) − MEMS- GC-EAG as well as other GC applications. This project aims to develop and lead to commercialization of the HT-MEMS flow controller to (1) implement chopper stabilization for GC-EAG, which holds the promise of improving the sensitivity of the current GC-EAG system by orders of magnitude; (2) explore applications of the instrument in broader chemical sensing areas, including other GC detectors beyond EAG and two dimensional GC (2D-GC). Apart from resulting publications and presentations at workshops and meetings, the technology will be disseminated through a partnership with GC equipment manufacturers and distributors.

美国宾夕法尼亚州立大学（Pennsylvania State University）获得了一项奖项，以开发一种用于气相色谱（GC）应用的微制造高温流动控制装置，该装置将有利于农业和林业更好地瞄准入侵物种和害虫。该装置将实现一种名为斩波调制天线（EAG）的技术，该技术利用气相色谱（GC）分离挥发性气味，并将昆虫触角作为检测器来识别对昆虫重要且能够被昆虫感知的特定化合物。经过数百万年的进化，昆虫的触角能够比人工化学传感器更灵敏、更特异地探测到某些化学物质。剪切调制GC-EAG方法将使用所提出的流量控制装置来调节气相色谱中的气体流量，并提高EAG的信噪比，从而使对行为重要的挥发性化学物质的检测灵敏度提高几个数量级。在其他气相色谱应用中使用该装置可以潜在地为一般化学传感社区做出贡献，并为环境监测，食品安全，疾病诊断等提供更灵敏的分析，从而使社会受益。教育计划包括学生培训和课程开发。该仪器还将纳入各种外联活动，包括PSU年度“大昆虫展”，每年参加该活动的人数通常超过8,000人。技术摘要：本研究的总体目标是开发一种高温微机电系统（MEMS）流量控制器（HT-MEMS流量控制器），其目的是在传统的气相色谱（GC）烤箱内操作，以启用旋翼调制天线图（EAG） &#8722；MEMS- GC- eag以及其他GC应用。该项目旨在开发并实现HT-MEMS流量控制器的商业化，以实现GC-EAG的斩波稳定，这有望将当前GC-EAG系统的灵敏度提高几个数量级；(2)探索该仪器在更广泛的化学传感领域的应用，包括除EAG和二维GC （2D-GC）之外的其他GC检测器。除了在研讨会和会议上发表出版物和演讲外，该技术还将通过与气相色谱设备制造商和分销商的合作伙伴关系进行传播。