Discovery and characterization of new classes of small regulatory RNAs in mammals

哺乳动物中新型小调控 RNA 的发现和表征

• 批准号: DP0988851
• 负责人: Prof John Mattick
• 金额: $ 41.59万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-09-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0988851
• 关键词: Discovery; characterization; new; classes; small

The project will reaffirm and enhance Australian leadership in the most rapidly developing area of molecular biological and genetic research, by the application of ultra high-throughput sequencing technologies to discovery of regulatory RNAs, thereby to identify the characteristics of important regulatory pathways that underpin mammalian development, brain function and species diversity. The results of this research will have wide implications and applications in biotechnology, genetic engineering, animal breeding, medical science and advanced informatics.

该项目将通过应用超高通量测序技术发现调控RNA，从而确定支持哺乳动物发育、脑功能和物种多样性的重要调控途径的特征，重申和加强澳大利亚在分子生物学和遗传研究这一发展最迅速的领域的领导地位。本研究的结果将在生物技术、基因工程、动物育种、医学科学和先进信息学等领域具有广泛的意义和应用。