The role of RNA editing by the brain-specific enzym ADAR3 in learning and memory

大脑特异性酶 ADAR3 进行的 RNA 编辑在学习和记忆中的作用

• 批准号: DP120100729
• 负责人: Prof John Mattick
• 金额: $ 35.84万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120100729
• 关键词: role; RNA; editing; brain; specific

Higher-order cognition sets us apart from other species but how this is achieved is still under debate. The project will test the idea, strongly supported by recent genomic analyses, that subtle changes in the sequences of RNA in response to environmental stimuli underpin this extraordinary ability.

更高层次的认知使我们有别于其他物种，但如何实现这一点仍在争论中。该项目将测试这一想法，最近的基因组分析有力地支持了这一想法，即RNA序列的细微变化对环境刺激的反应支撑了这种非凡的能力。