Center for Sustainable Nanotechnology

可持续纳米技术中心

• 批准号: 1503408
• 负责人: Robert Hamers
• 金额: $ 2000万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1503408&HistoricalAwards=false
• 关键词: Center; Sustainable; Nanotechnology

The Center for Sustainable Nanotechnology (CSN) enables fundamental studies of the specific molecular interactions expected to occur when the surfaces of engineered nanoparticles come into contact with biological interfaces and components. The chemical insight gained from molecular and mechanistic studies of nano-bio interactions is used to intentionally design nanomaterials that provide the desired technical functions while also minimizing potentially adverse consequences with the environment. CSN research leads to introduction of a new generation of safer nanomaterials that may impact multiple sectors of the economy including energy, transportation, electronics, food, and agriculture. The CSN prepares a new generation of scientific innovators by providing education and professional development opportunities focused on innovation, communication, leadership, and interdisciplinary scientific skills. CSN researchers actively encourage diversity within chemistry through CSN-run workshops on overcoming implicit bias, recruitment of graduate students and postdocs, and Center-sponsored research experiences for students and faculty from underrepresented groups as well as veteran undergraduates. CSN researchers encourage diversity in public engagement, develops and practices informal communication skills, and expands the highly successful sustainable-nano.com blog to include Spanish language content, K-12 activity materials, podcasts, and videos.CSN integrates experiments with computation in three integrated research focus areas (RFAs). RFA1 develops new materials with precisely controlled structure and properties, molecular-level characterization tools such as advanced non-linear optical methods and sub-diffraction imaging, and novel computational methods spanning length scales from nanometers to millimeters. RFA2 uses the RFA1 tool kit to understand, control, and predict how nanomaterials attach to, penetrate, and alter cell surfaces using lipid bilayers as model systems for cell membranes. RFA3 determines the molecular processes by which pristine and environmentally transformed nanomaterials interact with living systems with diverse cellular chemistries, ranging from single cell to multi-cellular organisms. The integration of these three RFAs enables the Center to establish how nanomaterial properties and behavior impact biological outcomes. This knowledge leads to reliable predictions of biological responses to existing and future nanomaterials and guides the design and synthesis of safe, sustainable nanomaterials. In pursuing the project goals, the CSN puts particular emphasis on the synthesis, characterization, and molecular-level interactions initiated by complex, composite nanomaterials that are being used in emerging and future nano-enabled commercial technologies.The Center for Sustainable Nanotechnology is funded as part of the Centers for Chemical Innovation (CCI) program.

可持续纳米技术中心（CSN）实现了预期在工程纳米颗粒的表面与生物界面和组件接触时预期发生的特定分子相互作用的基本研究。从纳米生物相互作用的分子和机理研究中获得的化学见解用于故意设计提供所需技术功能的纳米材料，同时还将对环境的潜在不利后果最小化。 CSN研究导致引入新一代的更安全的纳米材料，这些纳米材料可能会影响经济多个部门，包括能源，运输，电子，食品和农业。 CSN通过提供专注于创新，沟通，领导和跨学科科学技能的教育和专业发展机会来准备新一代的科学创新者。 CSN的研究人员通过CSN运营的研讨会积极地鼓励化学中的多样性，以克服隐性偏见，研究生和博士后的招聘，以及为学生和教职员工的中心研究经验，来自代表性不足的团体以及退伍军人本科生。 CSN的研究人员鼓励公众参与，发展和实践非正式的沟通技巧，并扩大了非常成功的可持续nano.com博客，包括西班牙语内容，K-12活动材料，播客和Videos.csn.csn将实验与三个集成研究重点领域（RFAS）（RFAS）中的计算集成在一起。 RFA1开发具有精确控制的结构和性能的新材料，分子级特征工具，例如先进的非线性光学方法和亚分形式成像，以及从纳米到毫米的长度尺度的新型计算方法。 RFA2使用RFA1工具套件来理解，控制和预测纳米材料如何使用脂质双层作为细胞膜模型系统附着，穿透和改变细胞表面。 RFA3确定了原始和环境转化的纳米材料与具有多种细胞化学的活体系相互作用的分子过程，从单细胞到多细胞生物。这三个RFA的整合使中心能够确定纳米材料特性和行为如何影响生物学结果。这些知识导致对现有纳米材料的生物学反应的可靠预测，并指导安全，可持续的纳米材料的设计和综合。在追求项目目标时，CSN特别强调了由复杂的，复合纳米材料在新兴和启用纳米型纳米型商业技术中使用的复杂的，复合纳米材料发起的综合和分子水平的相互作用。可持续纳米技术中心用于化学Innovation Innovation（CCCI）的一部分。

项目成果

Metalloid and metal oxide nanoparticles suppress Sudden Death Syndrome of soybean

类金属和金属氧化物纳米粒子抑制大豆猝死综合症

• DOI: 10.1021/acs.jafc.9b06082
• 发表时间: 2019
• 期刊: Journal of Agricultural and Food Chemistry
• 影响因子: 6.1
• 作者: Perez, Cristian;De La Torre Roche, Roberto;Zuverza-Mena, Nubia;Ma, Chuanxin;Shen, Yu;White, Jason C.;Pozza, Edson;Pozza, Adélia;Elmer, Wade
• 通讯作者: Elmer, Wade

Preferential interactions of primary amine-terminated quantum dots with membrane domain boundaries and lipid rafts revealed with nanometer resolution

• DOI: 10.1039/c9en00996e
• 发表时间: 2020-01
• 期刊: Environmental Science: Nano
• 作者: Arielle C. Mensch;Eric S. Melby;E. Laudadio;Isabel U. Foreman-Ortiz;Yongqian Zhang;A. Dohnalkova;Dehong Hu;J. Pedersen;R. Hamers;G. Orr

DFT and thermodynamics calculations of surface cation release in LiCoO2

• DOI: 10.1016/j.apsusc.2020.145865
• 发表时间: 2020-06-15
• 期刊: APPLIED SURFACE SCIENCE
• 影响因子: 6.7
• 作者: Abbaspour-Tamijani, Ali;Bennett, Joseph W.;Mason, Sara E.
• 通讯作者: Mason, Sara E.

Nickel enrichment of next-generation NMC nanomaterials alters material stability, causing unexpected dissolution behavior and observed toxicity to S. oneidensis MR-1 and D. magna

• DOI: 10.1039/c9en01074b
• 发表时间: 2020-02
• 期刊: Environmental science. Nano
• 作者: Joseph T. Buchman;Evan A. Bennett;Chenyu Wang;Ali Abbaspour Tamijani;J. Bennett;Blake G. Hudson;Curtis M. Green;Peter L. Clement;Bo Zhi;Austin H. Henke;E. Laudadio;S. Mason;R. Hamers;R. Klaper;C. Haynes

Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides

• DOI: 10.1039/c9en01304k
• 发表时间: 2020-06-01
• 期刊: ENVIRONMENTAL SCIENCE-NANO
• 影响因子: 7.3
• 作者: Bennett, Joseph W.;Jones, Diamond T.;Mason, Sara E.
• 通讯作者: Mason, Sara E.