UNS: The role of wave dynamics and of tri-leafleted valves in microflows

UNS：波浪动力学和三叶阀在微流中的作用

• 批准号: 1511414
• 负责人: Morteza Gharib
• 金额: $ 33.5万
• 依托单位: California Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1511414&HistoricalAwards=false
• 关键词: UNS; role; wave; dynamics; tri

1511414(Gharib)This proposal is about understanding the mechanism by which insects breath. This is a project at the interface of microfluidics and bio-inspired fluid dynamics that could lead to the development of pumps for microfluidic networks, like those utilized when one places a miniature laboratory on a computer chip. Both theory and sophisticated experiments are proposed.The goal is to investigate the bioflow environment around dragonfly nymphs that live underwater and seem to breath by generating a propagating wave through their body and by controlling the flow around their body with motion of their anal valve. The goals are to (1) elucidate the role of the wave in respiratory flow generation, and (2) study how the tri-leafleted anal valve controls the exhalatory and inhalatory flow. It is proposed to simultaneously measure four parameters: the kinematics of the hindgut chamber wall, the kinematics of the anal valve, and the flow inside and outside the chamber. Theory will be developed to describe this process, centered on the movement of internal waves between the tail and the midsection of the dragonfly. Sophisticated experiments involving Synchrotron X-Ray imaging at Argonne National Labs to visualize the internal flow in dragonfly larvae will be performed, while Particle Image Velocimetry (PIV) experiments will be conducted to examine the external flow. The nymph's pump can be viewed as a biological zero net mass flux (ZNMF) pump and results from the proposed work could lead to the design of ZNMF pumps with better flow generation and flow control. There are activities designed to reach out to the UCLA Community School, whose students are mostly underprivileged, first-generation college students. The PI will continue the production of research related spots that appear as YouTube videos reaching out to hundreds of thousands of people.

1511414（Gharib）这个提议是关于理解昆虫呼吸的机制。这是一个微流体和生物启发流体动力学接口的项目，可能会导致微流体网络泵的开发，就像在计算机芯片上放置微型实验室时使用的泵一样。理论和复杂的实验都被提出。目标是研究生活在水下的鳄鱼周围的生物流动环境，它们似乎通过在身体中产生传播波并通过肛门瓣膜的运动控制身体周围的流动来呼吸。目的是（1）阐明波在呼吸流量产生中的作用，（2）研究三叶肛门阀如何控制呼气和吸气流量。建议同时测量四个参数：后肠腔室壁的运动学，肛门阀的运动学，以及腔室内外的流动。理论将被发展来描述这个过程，集中在内部波的运动之间的尾巴和中段的尾巴。将在阿贡国家实验室进行复杂的实验，包括同步加速器X射线成像，以可视化幼虫的内部流动，同时将进行粒子图像测速（PIV）实验，以检查外部流动。若虫的泵可以被看作是一个生物零净质量流量（ZNMF）泵和所提出的工作的结果可能会导致ZNMF泵的设计更好的流量产生和流量控制。 有一些活动旨在接触加州大学洛杉矶分校社区学校，其学生大多是贫困，第一代大学生。PI将继续制作与研究相关的视频，这些视频将以YouTube视频的形式出现，并向数十万人传播。