EAGER: Evaporation of mucosalivary fluid in the context of disease transmission

1546990（Bourouiba）这是一个研究生物流体的分散和蒸发的建议，这些流体是剧烈排出的（如打喷嚏和咳嗽）。这些流体在病原体传播和疾病通过空气以及建筑物和车辆中的空气循环系统传播方面发挥着重要作用。拟议的研究将探讨流体动力学在疾病传播中所起的作用。研究的问题涉及几个流体动力学问题，包括多相流，湍流，小尺度表面张力为主的流动和弹性复杂的非牛顿流动。拟议的研究将具体检查，详细的实验测量，mucsoalivary液滴的蒸发过程中喷出的液滴和水滴的形式，在激烈的蒸发过程之间的差异。它还建议调查如何喷射机制的mucosalliative液滴在密集的喷嚏或咳嗽悬浮液影响他们的蒸发过程相比，他们的蒸发隔离或稀释悬浮液。基本的物理定律和数学建模将用于获得对几种疾病具有普遍适用性的见解。这项研究的结果可能会导致一个新的研究领域的发展：严格的流体动力学和流行病学的数学建模之间的领域。建议对学生进行指导，同时PI和她的团队还将与剑桥的麻省理工学院博物馆联系，以开展针对公众的活动。

1546990(Bourouiba)This is a proposal to study the dispersion and evaporation of biologiocal fluids that are violently emitted (as in sneezing and coughing). These fluids play an important role in pathogen propagation and the spreading out of disease through the air and through systems for circulating air in buildings and vehicles.The proposed research will explore the role played by fluid dynamics in disease transmission. The problems examined involve several fluid dynamics problems, including multiphase flows, turbulent flows, small-scale surface tension dominated flows and elastic complex and non-Newtonian flows. The proposed research will specifically examine, with detailed experimental measurements, the differences between the evaporation processes of mucsoalivary fluid droplets ejected during violent expirations in the form of droplets and those of water droplets. It is also proposed to investigate how the ejection mechanism of the mucosalivary fluid droplets in dense sneeze or cough suspensions affects their evaporation process when compared to their evaporation in isolation or dilute suspensions. Fundamental physical laws and mathematical modeling will be used to gain insights with general applicability for several diseases. Results from this research might lead to the development of a new area of research altogether: the area between rigorous fluid dynamics and mathematical modeling of epidemiology. Mentoring of students is proposed, while the PI and her team will also reach out to the MIT Museum in Cambridge for the development of activities that target the public.