Phase II I/UCRC Pennsylvania State University Site: Center for Health Organization Transformation

II期I/UCRC宾夕法尼亚州立大学研究中心：卫生组织转型中心美国医疗保健系统在科学和临床技术发展方面处于全球领先地位。然而，由于支出占国内生产总值的17.1%，在获得和质量方面存在着巨大差距，沿着的是发病率和死亡率大大低于其他工业化国家。CHOT的使命是推进循证医疗管理和临床实践中转型战略的知识和实践。变革性方法的开发需要来自医疗保健各个领域的合作伙伴的参与，包括IT提供商、系统解决方案提供商、护理提供商、保险公司和拥有大型医疗保健覆盖计划的雇主。认识到“一刀切”的医疗保健方法是不可持续的，这促使了个性化高级健康系统（PAWS）的建模、开发和部署。PAWS超越了医疗保健系统中现有的传统界限，从个性化的病人护理模式（从病人？的角度），个性化药物输送系统（从医疗保健决策者的角度）。CHOT是唯一一个专注于医疗保健创新的产学研合作研究中心。该中心的跨学科方法将提供综合和广泛适用的解决方案，并将加强下一代医疗保健政策专家，医生，护士和工程师的教育。本科生和研究生成为一个高性能的多学科组织，提供网络，领导和职业安置的生态系统的一部分。预计该中心的工作将提高卫生保健质量，更有效地利用卫生系统的财政和系统资源，同时为行业提供即时决策支持。CHOT已经确定了四个研究领域，以满足我们的成员以及医疗行业的需求：宏观系统创新;健康质量，安全性，可及性和效率;以患者为中心的护理和人口健康干预;电子健康记录和信息交换。个性化高级健康系统（PAWS）的基本主题是通过对基于价值的护理，基于时间驱动的活动成本计算，以人为本的护理，医疗设备设计和集成，急诊科基准，社区护理，远程医疗和健康以及精准医疗和精准健康的基础研究来实现的。七个研究项目的协调计划将得到系统工程研究方法的支持。特别是，系统思维和系统动力学方法将与模拟，数据分析和机器学习相结合，以开发可以为干预和创新的前瞻性评估提供信息的模型。为了弥合在实践/管理中学到/发现的东西与已经做的事情之间的差距，将采取知识转化为行动的举措，以便为提高这些项目的影响做好技术准备。

Phase II I/UCRC Pennsylvania State University Site: Center for Health Organization TransformationThe U.S. healthcare system is a global leader in terms of scientific and clinical technology development. However, with expenditures at 17.1% of the GDP, significant gaps in terms of access and quality exist, along with rates of morbidity and mortality that are substantially worse than other industrialized nations. The mission of CHOT is to advance the knowledge and practice of transformational strategies in evidenced-based healthcare management and clinical practice. The development of transformative approaches will necessitate involving partners from all sectors of healthcare including IT providers, systems solutions providers, care providers, insurers, and employers with large healthcare coverage programs. The realization that a "one-size-fits-all" approach to healthcare is unsustainable has motivated the modeling, development and deployment of personalized advanced wellness systems (PAWS). PAWS transcends traditional boundaries existing within healthcare systems, ranging from personalized patient care models (from a patient?s perspective), to personalized drug delivery systems (from a healthcare decision maker's perspective). CHOT is the only industry-university cooperative research center focused on innovations in healthcare delivery. The Center's interdisciplinary approach will deliver integrated and broadly applicable solutions and will enhance the education of the next generation of healthcare policy experts, physicians, nurses, and engineers. Undergraduate and graduate students become a part of a high-performing multidisciplinary organization that provides an ecosystem for networking, leadership, and career placement. It is expected that the work of the Center will result in improved health care quality and more effective use of financial and system resources in the health system, while providing immediate decision support to industry. CHOT has identified four research areas in order to meet the needs of our members as well as the healthcare industry: macro-systems innovation; health quality, safety, access, and efficiency; patient-centered care and population health interventions; electronic health records and information exchange. The underlying theme of personalized advanced wellness systems (PAWS) is achieved through fundamental research in value-based care, time-driven activity based costing, person-centered care, medical device design and integration, emergency department benchmarking, community paramedicine, telehealth and wellness, and precision medicine and precision health. A concerted plan of seven research projects will be supported by research methods in systems engineering. In particular, systems thinking and system dynamics methods will be combined with simulation, data analytics, and machine learning in order to develop models that can inform the prospective assessment of interventions and innovations. In order to bridge gap between what is learned/discovered and what is done in practice/ management, knowledge-to-action (KTA) initiatives will be pursued, with a view toward technology readiness in order to increase the impact of these projects.