I-Corps: Sustainable manufacturing of natural vanillin

I-Corps:天然香兰素的可持续生产

基本信息

  • 批准号:
    1640315
  • 负责人:
  • 金额:
    $ 5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-05-01 至 2016-10-31
  • 项目状态:
    已结题

项目摘要

Production of high value chemicals from biomass is an area of increasing interest, especially in the Flavor and Fragrance industry where there is a growing demand for natural and sustainable products. This I-Corps team has developed processes to produce natural ferulate from non-food biomass. Natural ferulate is important to the Flavor and Fragrance Industry as it is used to produce the highly desired natural vanilla. Vanilla is one of the most important products sold in the Flavor and Fragrance Industry. The global flavor and fragrance chemicals market is a $20 billion industry with continuing annual growth rate of 4.3%. At the present time, vanilla represents around $1 billion of this global market with a 13,000 metric ton production volume. Naturally derived vanilla is an important segment of the market and constitutes 2,400 metric tons of this volume. Successful commercialization of this technology would provide a route for domestic production of renewable and sustainable natural vanillin from non-food biomass sources.This team has developed proprietary technologies for selective upgrading of wood lignin to high value chemicals used in the flavor and fragrance industries. A new application of this technology seeks to produce natural ferulate from biomass, while simultaneously working to better understand the customer needs through the I-Corps discovery process. The goal of the discovery process is to validate the hypothesis that natural ferulate produced from non-food biomass will be a valuable product desired by producers of natural vanillin. The scope of the project includes over 100 interviews with relevant industry contacts to test the hypothesis. Methods employed will focus on interviews with members of the entire value chain including; biomass suppliers, producers of ferulate and vanillin, flavor and fragrance compounders and formulators, and distributors. This discovery work will provide essential data and understanding as the project advances in the prototype stage. Prototype scale-up will be conducted through a combination of already constructed in-house reactors, and will also utilize toll manufacturing. Data from the prototype scale-up will be used in combination with the data generated through I-Corps interviews to provide great insight into the commercial viability of the proposed process and recommendations for further scaling.
利用生物质生产高价值化学品是一个越来越受关注的领域,特别是在香精香料行业,对天然和可持续产品的需求不断增长。该 I-Corps 团队开发了利用非食品生物质生产天然阿魏酸的工艺。天然阿魏酸对于香精香料行业非常重要,因为它被用来生产非常理想的天然香草。香草是香精香料行业最重要的产品之一。全球香精香料化学品市场规模达 200 亿美元,年增长率持续达到 4.3%。 目前,香草精产量为 13,000 吨,占全球市场价值约 10 亿美元。天然香草是市场的一个重要部分,占该市场的 2,400 吨。该技术的成功商业化将为国内从非食品生物质来源生产可再生和可持续的天然香兰素提供一条途径。该团队开发了专有技术,用于选择性地将木质素升级为用于香精香料行业的高价值化学品。该技术的一项新应用旨在从生物质中生产天然阿魏酸,同时通过 I-Corps 发现过程更好地了解客户需求。该发现过程的目标是验证以下假设:由非食品生物质生产的天然阿魏酸将成为天然香兰素生产商所需的有价值的产品。该项目的范围包括对相关行业联系人进行 100 多次访谈,以检验该假设。所采用的方法将侧重于对整个价值链成员的访谈,包括:生物质供应商、阿魏酸盐和香草醛生产商、香精香料复合商和配方设计师以及分销商。随着项目在原型阶段的进展,这项发现工作将提供必要的数据和理解。原型放大将通过已建造的内部反应器的组合进行,并且还将利用委托制造。来自原型放大的数据将与通过 I-Corps 访谈生成的数据结合使用,以深入了解所提议流程的商业可行性以及进一步扩展的建议。

项目成果

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Mahdi Abu-Omar其他文献

Mahdi Abu-Omar的其他文献

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{{ truncateString('Mahdi Abu-Omar', 18)}}的其他基金

CAS: Catalytic funneling and upgrading of biomass-derived phenols and polyols
CAS:生物质衍生酚和多元醇的催化漏斗和升级
  • 批准号:
    2154333
  • 财政年份:
    2022
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Catalytic Oxidations with Lignin-Based Ligands
木质素基配体的催化氧化
  • 批准号:
    1856753
  • 财政年份:
    2019
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Bioinspired and Sustainable Catalysis for Chlorite Conversion and Dioxygen Reduction
亚氯酸盐转化和分子氧还原的仿生和可持续催化
  • 批准号:
    1646790
  • 财政年份:
    2016
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
Bioinspired and Sustainable Catalysis for Chlorite Conversion and Dioxygen Reduction
亚氯酸盐转化和分子氧还原的仿生和可持续催化
  • 批准号:
    1463900
  • 财政年份:
    2015
  • 资助金额:
    $ 5万
  • 项目类别:
    Standard Grant
High-Valent Imido and Oxo Complexes in Electron Transfer, Atom Transfer, and Chlorite Catalysis
电子转移、原子转移和亚氯酸盐催化中的高价亚氨基和氧配合物
  • 批准号:
    1110475
  • 财政年份:
    2011
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
Mechanistic Studies of Oxygen Evolution and Hydrogen Atom Transfer in Enzymes and Biomimatic Models
酶和仿生模型中析氧和氢原子转移的机理研究
  • 批准号:
    0749572
  • 财政年份:
    2008
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
Bioinorganic Enzymology of a Non-Heme Iron Hydroxylase
非血红素铁羟化酶的生物无机酶学
  • 批准号:
    0502391
  • 财政年份:
    2005
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
Probing the Mechanism and Structure-Function Relations in Phenylalanine Hydroxylase
苯丙氨酸羟化酶的作用机制及构效关系探讨
  • 批准号:
    0434637
  • 财政年份:
    2004
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
Probing the Mechanism and Structure-Function Relations in Phenylalanine Hydroxylase
苯丙氨酸羟化酶的作用机制及构效关系探讨
  • 批准号:
    0208682
  • 财政年份:
    2002
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant
CAREER: Molecular Rhenium(V) Oxotransferases
职业:分子铼(V) 氧化转移酶
  • 批准号:
    9874857
  • 财政年份:
    1999
  • 资助金额:
    $ 5万
  • 项目类别:
    Continuing Grant

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REU 网站:可持续制造夏季学院
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    2348993
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