Evolutionary Responses to Global Changes in Salinity and Temperature
对全球盐度和温度变化的进化反应
基本信息
- 批准号:1658517
- 负责人:
- 金额:$ 85.29万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-03-15 至 2022-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Drastic changes in the global water cycle and increases in ice melt are causing the freshening of Northern coastal seas. The combination of both reduced salinity and increased temperature will likely act in concert to reduce populations of estuarine and marine organisms. Data indicate that reduced salinity and high temperature would each increase the energy costs as well as reduce survival and reproduction of the common copepod Eurytemora affinis. This project will examine the joint effects of salinity reduction and temperature increase on the evolutionary responses of populations of E. affinis in the wild, as well as in selection experiments in the laboratory. This study will provide novel insights into responses of organisms to climate change, as no study has analyzed the joint impacts of salinity and temperature on evolutionary responses, and relatively few studies have examined the impacts of declining salinity. In general, how selection acts at the whole genome level is not well understood, particularly for non-model organisms. As a dominant estuarine copepod, E. affinis is among the most important species sustaining coastal food webs and fisheries in the Northern Hemisphere, such as salmon, herring, and anchovy. Thus, insights into its evolutionary responses with changing climate have important implications for sustainability of fisheries and food security. Two graduate students from historically underrepresented groups will be trained during this project. The project will have additional societal benefits, including development of educational modules for K-12 students and international collaboration. This study will address the following questions: (1) To what extent could populations evolve in response to salinity and temperature change, and what are the fitness and physiological costs? (2) How will populations respond to the impacts of salinity-temperature interactions? (3) Do wild populations show evidence of natural selection in response to salinity and temperature? To analyze the evolutionary responses of E. affinis populations to the coupled impacts of salinity and temperature, the investigator will perform laboratory selection experiments and population genomic surveys of wild populations. Selection experiments constitute powerful tools for determining the rate, trajectory, and limits of adaptation. During laboratory selection, evolutionary shifts in fitness-related traits and genomic expression will be examined, as well as genomic signatures of selection in response to low salinity and high temperature selection regimes. The investigator will also conduct population genomic sequencing of E. affinis populations that reside along salinity and temperature gradients in the St. Lawrence and Baltic Sea, and identify genes that show signatures of selection. The project will determine whether the loci that show signatures of selection in the wild populations are the same as those favored during laboratory selection. This reproducibility will provide greater confidence that the genes involved in adaptation to salinity and/or temperature have been captured.
全球水循环的剧烈变化和冰融化的增加正在导致北部沿海海域变新鲜。盐度的降低和温度的升高可能会共同减少河口和海洋生物的数量。数据表明,降低盐度和高温都会增加能量消耗,降低普通桡足动物的存活率和繁殖能力。本项目将研究盐度降低和温度升高对野生affinis种群进化反应的共同影响,以及在实验室的选择实验中。这项研究将为生物对气候变化的响应提供新的见解,因为没有研究分析盐度和温度对进化响应的共同影响,而且相对较少的研究研究了盐度下降的影响。一般来说,选择是如何在整个基因组水平上起作用的还不是很清楚,特别是对于非模式生物。作为一种优势的河口桡足类动物,与鲑鱼、鲱鱼和凤尾鱼一样,是维持北半球沿海食物网和渔业的最重要物种之一。因此,深入了解其对气候变化的进化反应对渔业的可持续性和粮食安全具有重要意义。两名来自历史上代表性不足的群体的研究生将在这个项目中接受培训。该项目将带来额外的社会效益,包括为K-12学生开发教育模块和国际合作。本研究将解决以下问题:(1)种群对盐度和温度变化的响应程度,以及适应性和生理成本是什么?(2)种群如何响应盐度-温度相互作用的影响?(3)野生种群是否表现出对盐度和温度的自然选择?为了分析亲和沙蚕种群对盐度和温度耦合影响的进化响应,研究者将进行实验室选择实验和野生种群基因组调查。选择实验是确定适应速度、轨迹和极限的有力工具。在实验室选择过程中,将研究适应性相关性状和基因组表达的进化转变,以及低盐度和高温选择机制下选择的基因组特征。研究人员还将对生活在圣劳伦斯海和波罗的海沿盐度和温度梯度的亲和鲈种群进行种群基因组测序,并确定显示选择特征的基因。该项目将确定在野生种群中显示出选择特征的位点是否与在实验室选择中受到青睐的位点相同。这种可重复性将提供更大的信心,即参与适应盐度和/或温度的基因已被捕获。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The Legs Have It: In Situ Expression of Ion Transporters V-Type H + -ATPase and Na + /K + -ATPase in the Osmoregulatory Leg Organs of the Invading Copepod Eurytemora affinis
腿部有它:离子转运蛋白 V 型 H -ATP 酶和 Na /K -ATP 酶在入侵桡足类 Eurytemora affinis 的渗透调节腿部器官中的原位表达
- DOI:10.1086/686323
- 发表时间:2016
- 期刊:
- 影响因子:1.6
- 作者:Gerber, Lucie;Lee, Carol Eunmi;Grousset, Evelyse;Blondeau-Bidet, Eva;Boucheker, Nesrine Boudour;Lorin-Nebel, Catherine;Charmantier-Daures, Mireille;Charmantier, Guy
- 通讯作者:Charmantier, Guy
Ion Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod
离子转运蛋白基因家族作为桡足类盐度转变过程中自然选择的生理目标
- DOI:10.1152/physiol.00009.2021
- 发表时间:2021
- 期刊:
- 影响因子:8.4
- 作者:Lee, Carol Eunmi
- 通讯作者:Lee, Carol Eunmi
Recognizing Salinity Threats in the Climate Crisis
认识气候危机中的盐度威胁
- DOI:10.1093/icb/icac069
- 发表时间:2022
- 期刊:
- 影响因子:2.6
- 作者:Lee, Carol Eunmi;Downey, Kala;Colby, Rebecca Smith;Freire, Carolina A.;Nichols, Sarah;Burgess, Michael N.;Judy, Kathryn J.
- 通讯作者:Judy, Kathryn J.
Evolutionary origins of genomic adaptations in an invasive copepod
- DOI:10.1038/s41559-020-1201-y
- 发表时间:2020-06-22
- 期刊:
- 影响因子:16.8
- 作者:Ben Stern, David;Lee, Carol Eunmi
- 通讯作者:Lee, Carol Eunmi
Testing for beneficial reversal of dominance during salinity shifts in the invasive copepod Eurytemora affinis , and implications for the maintenance of genetic variation
测试入侵桡足动物Eurytemora affinis在盐度变化过程中优势地位的有益逆转,以及对维持遗传变异的影响。
- DOI:10.1111/evo.12502
- 发表时间:2014
- 期刊:
- 影响因子:3.3
- 作者:Posavi, Marijan;Gelembiuk, Gregory William;Larget, Bret;Lee, Carol Eunmi
- 通讯作者:Lee, Carol Eunmi
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Carol Lee其他文献
Influence of stress factors on intestinal epithelial injury and regeneration
应激因素对肠上皮损伤及再生的影响
- DOI:
- 发表时间:
2018 - 期刊:
- 影响因子:0
- 作者:
Carol Lee;Adam Minich;Bo Li;H. Miyake;Shogo Seo;A. Pierro - 通讯作者:
A. Pierro
Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma
奥沙利铂诱导肝癌细胞焦亡并增强抗肝癌抗肿瘤免疫
- DOI:
10.1038/s41416-024-02908-z - 发表时间:
2025-01-02 - 期刊:
- 影响因子:6.800
- 作者:
Min Deng;Rongce Zhao;Hao Zou;Renguo Guan;Jiongliang Wang;Carol Lee;Benyi He;Jing Zhou;Shaohua Li;Wei Wei;Hao Cai;Rongping Guo - 通讯作者:
Rongping Guo
UNIFIED: Understanding New Information from Emergency Departments Involved in the San Bernardino Terrorist Attack
UNIFIED:了解参与圣贝纳迪诺恐怖袭击的急诊部门的新信息
- DOI:
10.5811/westjem.2019.11.43437 - 发表时间:
2020 - 期刊:
- 影响因子:3.1
- 作者:
Dustin Smith;E. L. Walters;Ellen Reibling;Darren Brockie;Carol Lee;Michael Neeki;Humberto Ochoa;Travis Henson;James Fisgus;Tammi Thomas - 通讯作者:
Tammi Thomas
Early maternal separation induces alterations of colonic epithelial permeability and morphology
早期母体分离导致结肠上皮通透性和形态的改变
- DOI:
- 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
Bo Li;Carol Lee;A. Zani;Elke Zani;W. Ip;Lijun Chi;P. Olguin;T. Gonska;A. Pierro - 通讯作者:
A. Pierro
Burn Injuries resulting from Methamphetamine and Honey Oil Explosions: A retrospective cohort study.
甲基苯丙胺和蜂蜜油爆炸造成的烧伤:一项回顾性队列研究。
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:1.4
- 作者:
M. Neeki;F. Dong;Dania Youssef;Benfie Liu;Carol Lee;M. Burgett;E. Rippe;David Wong;R. Borger - 通讯作者:
R. Borger
Carol Lee的其他文献
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{{ truncateString('Carol Lee', 18)}}的其他基金
BEE: Evolutionary Responses to Global Change - Linking Genotype with Phenotype to Model Future Demography and Range Expansions
BEE:对全球变化的进化反应 - 将基因型与表型联系起来以模拟未来的人口统计和范围扩展
- 批准号:
2055356 - 财政年份:2021
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
DIMENSIONS: Collaborative Research - Uncovering the novel diversity of the copepod microbiome and its effect on habitat invasions by the copepod host
维度:合作研究——揭示桡足类微生物组的新多样性及其对桡足类宿主栖息地入侵的影响
- 批准号:
1046372 - 财政年份:2010
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
RAPID: Rapid Evolutionary Response of Coastal Copepods to the Gulf Oil Spill
RAPID:沿海桡足类对海湾漏油事件的快速进化反应
- 批准号:
1050565 - 财政年份:2010
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
Exploring Genomic Targets of Selection during Parallel Niche Expansions
探索平行生态位扩展期间选择的基因组目标
- 批准号:
0745828 - 财政年份:2008
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
Evolutionary Potential of Invasive Populations
入侵种群的进化潜力
- 批准号:
0448827 - 财政年份:2005
- 资助金额:
$ 85.29万 - 项目类别:
Continuing Grant
SLC Catalyst: Culture, Learning, and Development
SLC 催化剂:文化、学习和发展
- 批准号:
0350324 - 财政年份:2003
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
Research Starter Grant: Evolutionary History of Invasions by the Zebra Mussel, Dreissena polymorpha
研究启动资助:斑马贻贝(Dreissena polymorpha)入侵的进化史
- 批准号:
0130543 - 财政年份:2001
- 资助金额:
$ 85.29万 - 项目类别:
Standard Grant
Postdoctoral Research Fellowship in Biosciences Related to the Environment for FY 1997
1997财年环境相关生物科学博士后研究奖学金
- 批准号:
9750291 - 财政年份:1998
- 资助金额:
$ 85.29万 - 项目类别:
Fellowship Award
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