IRES: Training Next Generation Researchers in Advanced Magnetic Resonance at Chemistry Interfaces

目标是在德国应用化学的背景下，培养一批早期化学和化学工程研究生，使他们能够完成由合成（Make）、创新测量（Measure）、系统建模和可持续运行（Model）组成的M3循环。这个M3循环在现代化学中至关重要，因为它代表了实现化学合成快速发展和理解化学转化的最有效方法，但这个循环在美国化学科学课程中并没有广泛实施。这次教育游览将训练学生更好地理解学术界和工业界之间的相互关系，以及他们将在全球经济中遇到的跨文化差异。我们的目标是利用这种教育方法来吸引那些希望专注于创新测量的高积极性博士生，同时帮助他们与更广泛的M3周期概念联系起来，从而作为跨学科和跨文化大使为社会做出贡献。在化学教育中有一个相互交织的需求：(1)培养下一代先进和新的化学测量技术专家；(2)教他们如何在化学最感兴趣的问题的背景下，在科学发现和社会需求的联系下，进行、观察和展示他们的专业和新颖的测量方法。在M3界面进行研究的研究生无疑会以不同的方式思考他们所在领域的领导者，并更好地理解与德国化学景观的联系。M3教育经验的成功有望为化学研究生课程的新课程和重点的发展提供信息。来自加州大学圣巴巴拉分校（UCSB） （Han）、加州大学伯克利分校（UCB）（Reimer）、加州大学洛杉矶分校（UCLA）（Bouchard）和德国亚琛工业大学（Rheinisch-Westfälische Technische Hochschule）（RWTH）的高级磁共振专家组联合起来，将他们的先进分析工具汇集在一起，在三向M3循环中综合解决问题。与化学和工程同事协同合作，集中精力培养一批研究生。亚琛工业大学的几个研究小组是追求这一教育努力的理想合作伙伴，不仅因为亚琛工业大学在建立化学工程合作伙伴关系方面排名第一，而且因为加州大学洛杉矶分校/UCSB/UCB与亚琛工业大学的pi之间存在强大的多pi合作，IRES研究员可以沉浸其中。每年将选拔5-7名研究生，并在其博士学习的第一年招募他们，目标是在整个研究生生涯中利用支持和协作支持，将他们的研究和培训整合到M3周期中。这些被选中的学生将在出发前准备每周的德语语言和文化在线课程。IRES学员将在出发前在UCSB参加一个培训会议，并在第一年博士学习结束后的夏天前往亚琛。预期的结果是，研究生已经获得了如何加速化学物质、材料和系统参数的发现和分类，以及如何在给定一组起始化学物质的情况下设计反应途径的实践经验。这一学习过程和演变将在年度研讨会上分享，届时将有现任和过去的IRES研究员参加。将评估IRES研究员计划的有效性，并通过社交媒体保持他们在队列和合作者中的专业联系。

Nontechnical AbstractOur goal is to train a cohort of early-stage chemistry and chemical engineering graduate students to the connecting M3 cycle consisting of synthesis (Make), innovative measurements (Measure) and system modeling and sustainable operation (Model), in the context of applied chemistry in Germany. This M3 cycle is critically important in modern chemistry as it represents the most effective way to achieve rapid advances in chemical synthesis and the understanding of chemical transformations, yet this cycle is not broadly implemented in the U.S. chemical science curriculum. The proposed educational excursion will train students to better understand the interrelationship between academia and industry, as well as intercultural differences that they will encounter in a global economy. We aim to use this educational approach as an attractor to recruit highly motivated doctoral students who wish to specialize in innovative measurements, while helping them connect to the broader concept of the M3 cycle, and so contribute to society as interdisciplinary and intercultural ambassadors. There is an intertwined need in chemistry education: (i) to train the next generation experts in advanced and new chemical measurement technology, and (ii) to teach them how to conduct, view and present their specialized and novel measurement methods in the context of problems of utmost interest to chemistry, at the nexus of science discovery and societal needs. Graduate students who have carried out their studies at the M3 interface will undoubtedly think differently as leaders in their field and have a better understanding to connect to the German chemistry landscape. The successes of the M3 educational experience is expected to help inform the development of new courses and emphases for chemistry graduate programs.Technical AbstractExpert groups in advanced magnetic resonance at University of California-Santa Barbara (UCSB) (Han), University of California-Berkeley (UCB)(Reimer), University of California-Los Angeles (UCLA)(Bouchard) and the Rheinisch-Westfälische Technische Hochschule (RWTH)in Aachen, Germany (Blümich) joined together to pool their advanced analytical tools to work on integrated problem-solving in a three-way M3 cycle, in synergistic collaboration with chemistry and engineering colleagues to concentrate their efforts on the training of a cohort of graduate students. Several research groups at the RWTH Aachen University are ideal partners to pursue this educational endeavor, not only because the RWTH is ranked #1 in forging chemistry-engineering partnerships, but also because there are strong existing multi-PI collaborations between the UCLA/UCSB/UCB and RWTH PIs that the IRES fellows can immerse themselves in. A cohort of 5-7 graduate students per year will be selected and recruited in the first year of their doctoral studies, with the goal to integrate their research and training in the M3 cycle throughout their entire graduate career with leveraging support and collaborative backing. These select students will be prepared pre-departure with weekly online sessions on the German language and culture. The IRES cohort will gather at UCSB for an orientation conference ahead of their departure and travel to Aachen in the summer following the first year of their doctoral studies. The expected outcome is that the graduate students have gained hands-on experience on how to accelerate the discovery and triaging of chemical, materials and system parameters and how to design reaction pathways given a set of starting chemicals. This learning process and evolution will be shared at an annual workshop involving current and past IRES fellows. The effectiveness of the IRES fellows program will be evaluated, and their professional connection within the cohort and the collaborators maintained through social media.