Division plane orientation in plant cells.

植物细胞的分裂面方向。

基本信息

  • 批准号:
    1716972
  • 负责人:
  • 金额:
    $ 87.03万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-08-01 至 2021-06-30
  • 项目状态:
    已结题

项目摘要

This research improves the public well-being through development of critical knowledge using the important crop maize and other plants to understand cell division and its role in development. A critical aspect of cell division is the orientation of the division plane or the axis at which division occurs. When and where the cell positions the division plane has significant impact on the overall organization of the plant. Although the importance of regulated division plane orientation during plant and animal development is well known, the mechanisms that controls this process are not well understood. Understanding how plants regulate division plane orientation will make it possible to harness this feature of plant development for next generation crop improvement. Broader Impact activities will include providing a research experience to freshman students along with research opportunities to underrepresented minority students. Correct division plane orientation, or the establishment of the axis on which a cell divides, is critical for development and growth in many organisms. This research will determine the biochemical and in vivo function of proteins responsible for controlling division plane orientation in the monocot crop maize. The experimental approaches include single-molecule protein and microtubule dynamics, live cell imaging, structure versus function analysis, mathematical modeling, and reverse and forward genetics. The expected outcome of this research is an understanding as to how a protein essential for division plane orientation alters microtubule binding and dynamics, identification of amino acids critical for this protein's function, as well as quantification of the relative contributions of cell shape and local and global interactions to division plane orientation. Finally, new proteins will be identified that promote the proper division plane orientation. Understanding how plants place their division planes may provide insight into controlling division orientation to increase yield of valuable crop plant products.
这项研究通过发展重要作物玉米和其他植物的关键知识来了解细胞分裂及其在发育中的作用,从而改善公众福祉。细胞分裂的一个关键方面是分裂平面或分裂发生的轴的方向。细胞何时以及在何处定位分割平面对工厂的整体组织有重大影响。虽然在植物和动物发育过程中调控分裂平面方向的重要性是众所周知的,但控制这一过程的机制还不清楚。了解植物如何调节分裂平面的方向将使利用植物发育的这一特征来改良下一代作物成为可能。 更广泛的影响活动将包括提供一个研究经验,以新生沿着研究机会,以代表性不足的少数民族学生。正确的分裂面方向,或细胞分裂轴的建立,对许多生物体的发育和生长至关重要。这项研究将确定在单子叶作物玉米中负责控制分裂平面方向的蛋白质的生物化学和体内功能。实验方法包括单分子蛋白质和微管动力学,活细胞成像,结构与功能分析,数学建模,以及反向和正向遗传学。这项研究的预期成果是了解分裂平面方向所必需的蛋白质如何改变微管结合和动力学,鉴定对该蛋白质功能至关重要的氨基酸,以及量化细胞形状和局部和全局相互作用对分裂平面方向的相对贡献。最后,新的蛋白质将被确定,促进适当的分裂平面的方向。了解植物如何放置它们的分裂平面可以提供对控制分裂取向以增加有价值的作物植物产品的产量的洞察。

项目成果

期刊论文数量(11)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Staining Maize Epidermal Leaf Peels with Toluidine Blue O
用甲苯胺蓝 O 染色玉米表皮叶皮
  • DOI:
    10.21769/bioprotoc.3214
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0.8
  • 作者:
    Bellinger, Marschal;Sidhu, Sukhmani;Rasmussen, Carolyn
  • 通讯作者:
    Rasmussen, Carolyn
Predicting Division Planes of Three-Dimensional Cells by Soap-Film Minimization
  • DOI:
    10.1105/tpc.18.00401
  • 发表时间:
    2018-10-01
  • 期刊:
  • 影响因子:
    11.6
  • 作者:
    Martinez, Pablo;Allsman, Lindy A.;Rasmussen, Carolyn G.
  • 通讯作者:
    Rasmussen, Carolyn G.
Using Seed Chipping to Genotype Maize Kernels
使用种子切片对玉米粒进行基因分型
  • DOI:
    10.21769/bioprotoc.3553
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    0.8
  • 作者:
    Mills, Alison;Allsman, Lindy;Leon, Sareen;Rasmussen, Carolyn
  • 通讯作者:
    Rasmussen, Carolyn
In vitro Conditions for Dark Growth and Analysis of Maize Seedlings
玉米幼苗的体外暗生长条件及分析
  • DOI:
    10.21769/bioprotoc.3555
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    0.8
  • 作者:
    Farrow, Jeffrey;Bellinger, Marschal;Rasmussen, Carolyn
  • 通讯作者:
    Rasmussen, Carolyn
Glue Impressions of Maize Leaves and Their Use in Classifying Mutants
玉米叶的胶印及其在突变体分类中的应用
  • DOI:
    10.21769/bioprotoc.3209
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    0.8
  • 作者:
    Allsman, Lindy;Dieffenbacher, Raquel;Rasmussen, Carolyn
  • 通讯作者:
    Rasmussen, Carolyn
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Carolyn Rasmussen其他文献

PIN2-mediated self-organizing transient auxin flow contributes to auxin maxima at the tip of Arabidopsis cotyledons
PIN2 介导的自组织瞬时生长素流有助于拟南芥子叶顶端的生长素最大值
  • DOI:
    10.1038/s41467-024-55480-8
  • 发表时间:
    2025-02-05
  • 期刊:
  • 影响因子:
    15.700
  • 作者:
    Patricio Pérez-Henríquez;Shingo Nagawa;Zhongchi Liu;Xue Pan;Marta Michniewicz;Wenxin Tang;Carolyn Rasmussen;Xinping Cui;Jaimie Van Norman;Lucia Strader;Zhenbiao Yang
  • 通讯作者:
    Zhenbiao Yang

Carolyn Rasmussen的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Carolyn Rasmussen', 18)}}的其他基金

REU Site: Research Experiences for Undergraduates in Next-generation Cell Biology of Plants and Plant Pathogens
REU网站:下一代植物细胞生物学和植物病原体本科生研究经验
  • 批准号:
    2051131
  • 财政年份:
    2021
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
CAREER: Mechanisms of division plane orientation in plant cells
职业:植物细胞分裂面方向的机制
  • 批准号:
    1942734
  • 财政年份:
    2020
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
Division Plane Orientation in Plant Cells
植物细胞的分割面方向
  • 批准号:
    1505848
  • 财政年份:
    2014
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
Division Plane Orientation in Plant Cells
植物细胞的分割面方向
  • 批准号:
    1244202
  • 财政年份:
    2013
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant

相似海外基金

Development and Verification of Variable Reinforced Orientation Composite Enabling In-Plane Super Elasticity and Out-of-Plane High Strength
可变增强取向复合材料的开发和验证,实现面内超弹性和面外高强度
  • 批准号:
    23K03594
  • 财政年份:
    2023
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Investigation on orientation mechanism of basal plane of graphite
石墨基面取向机制研究
  • 批准号:
    22H01833
  • 财政年份:
    2022
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Identifying mechanisms for stem cell division plane orientation in plants
识别植物干细胞分裂面方向的机制
  • 批准号:
    2594262
  • 财政年份:
    2021
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Studentship
CAREER: Mechanisms of division plane orientation in plant cells
职业:植物细胞分裂面方向的机制
  • 批准号:
    1942734
  • 财政年份:
    2020
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
PZT thin film with perfectly in-plane polarization orientation for 5G high-speed communication technology
用于5G高速通信技术的具有完美面内偏振取向的PZT薄膜
  • 批准号:
    20K15372
  • 财政年份:
    2020
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
CAREER: genetic approach to identifying proteins necessary for division plane orientation during plant development
职业:通过遗传方法识别植物发育过程中分割平面方向所需的蛋白质
  • 批准号:
    1350874
  • 财政年份:
    2014
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
Division Plane Orientation in Plant Cells
植物细胞的分割面方向
  • 批准号:
    1505848
  • 财政年份:
    2014
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
Division Plane Orientation in Plant Cells
植物细胞的分割面方向
  • 批准号:
    1244202
  • 财政年份:
    2013
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Continuing Grant
STRUCTURAL DESIGN OF HIGHLY ORIENTED LAYERED-MATERIAL FOR LITHIUM ION SECONDARY BATTERIES
锂离子二次电池高取向层状材料的结构设计
  • 批准号:
    15360510
  • 财政年份:
    2003
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
NER: Deposition of Molecular Nanostructures with Controlled in-plane Orientation
NER:具有受控面内取向的分子纳米结构的沉积
  • 批准号:
    0210058
  • 财政年份:
    2002
  • 资助金额:
    $ 87.03万
  • 项目类别:
    Standard Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了