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MRI: Acquisition of the First 800 MHz NMR Spectrometer with a Cryogenically Cooled Probe in the State of Oklahoma for Interdisciplinary Research and Training

MRI: Acquisition of the First 800 MHz NMR Spectrometer with a Cryogenically Cooled Probe in the State of Oklahoma for Interdisciplinary Research and Training
MRI:在俄克拉荷马州采购第一台带有低温冷却探头的 800 MHz NMR 波谱仪,用于跨学科研究和培训
批准号:
1726397
负责人:
Smita Mohanty
金额:
$228.86万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-09-01 至 2023-08-31

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中文摘要
翻译
在主要研究仪器(MRI)计划的支持下,俄克拉荷马州州立大学获得了一个带有冷冻探针的800 MHz NMR仪器的奖励。 该仪器将被安置在俄克拉荷马州全州共享核磁共振设施,以确保它是在俄克拉荷马州和周边地区的研究人员访问。新的光谱仪将支持现代最先进的NMR技术的下一代研究人员的培训。俄克拉荷马州州立大学正在通过课程和独立研究积极追求动手本科研究培训。此外,化学系的项目,如国家科学基金会支持的“本科生研究经验(REU)”,允许在全国范围内招收本科生。少数民族本科生通过各种本科课程,如俄克拉荷马州路易斯斯托克斯少数民族参与联盟(OK-LSAMP)招募研究。核磁共振(NMR)光谱是科学家可用于阐明重要分子结构的最强大的科学技术之一。该仪器支持的项目涵盖从化学生物学到蛋白质结构和功能、蛋白质动力学、RNA/DNA结构、复杂碳水化合物结构、新型聚合物设计以及药物设计过程中的小复杂分子表征。新的核磁共振是化学生物学,结构生物学,生物化学,分子生物学,微生物学和聚合物科学研究人员在整个俄克拉荷马州和周边地区的一个重要资源。这些研究和教学工作的结果将通过学生和教师积极参与科学会议,研讨会和讲习班,同行评议的出版物和沉积的生物分子的原子坐标到蛋白质数据库(PDB)传播。
英文摘要
With support from the Major Research Instrumentation (MRI) Program, an award has been made to Oklahoma State University for the acquisition of a 800 MHz NMR instrument with a cryoprobe. This instrument will be housed in the Oklahoma Statewide Shared NMR Facility to ensure that it is accessible to researchers in Oklahoma and the surrounding region. The new spectrometer will support the training of the next generation of researchers in modern state-of-the-art NMR techniques. Oklahoma State University is aggressively pursing hands-on undergraduate research training through courses, and independent research. In addition, programs in the Chemistry Department such as "Research Experience for Undergraduate Students (REU)" supported by National Science Foundation allows recruitment of undergraduate students across the country. Minority undergraduate students are recruited for research through various undergraduate programs such as the Oklahoma Louis Stokes Alliance for Minority Participation (OK-LSAMP). Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful scientific techniques that is available to scientist for the elucidation of the structure of important molecules. Projects supported by this new instrument span the range from Chemical Biology to protein structure and function, protein dynamics, RNA/DNA structure, complex carbohydrate structure, design of novel polymer, and small complex molecules characterization during the process of drug design. The new NMR is an essential resource for researchers in Chemical Biology, Structural Biology, Biochemistry, Molecular Biology, Microbiology, and Polymer Science across Oklahoma and the surrounding region. The results of these research and teaching efforts will be disseminated through active participation of students and faculty at scientific conferences, symposia and workshops, peer-reviewed publications and the deposition of atomic coordinates of biomolecules to the Protein Data Bank (PDB).
期刊论文(18)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1261/rna.059865.116
发表时间: 2017-05-01
期刊: RNA
影响因子: 4.5
作者: [Phan, Andy, Mailey, Katherine, Schroeder, Susan J.]
通讯作者: Schroeder, Susan J.
NMR and MD simulations reveal the impact of the V23D mutation on the function of yeast oligosaccharyltransferase subunit Ost4
NMR 和 MD 模拟揭示了 V23D 突变对酵母寡糖转移酶亚基 Ost4 功能的影响
DOI: 10.1093/glycob/cwab002
发表时间: 2021
期刊: Glycobiology
影响因子: 4.3
作者: [Chaudhary, Bharat P, Zoetewey, David L, McCullagh, Martin J, Mohanty, Smita]
通讯作者: Mohanty, Smita
DOI: 10.1007/s12104-023-10145-3
发表时间: 2023-07-27
期刊: BIOMOLECULAR NMR ASSIGNMENTS
影响因子: 0.9
作者: [Al-Danoon,Omar, Mohanty,Smita]
通讯作者: Mohanty,Smita
DOI: 10.1007/s12104-020-09930-1
发表时间: 2020-04-01
期刊: BIOMOLECULAR NMR ASSIGNMENTS
影响因子: 0.9
作者: [Dahal, Salik R., Lewellen, Jacob L., Mohanty, Smita]
通讯作者: Mohanty, Smita
9
    Chemical Sensing: Linking sequence, mechanisms and inhibition
    • 批准号:
      1807722
    • 项目类别:
      Standard Grant
    • 资助金额:
      $63.0万
    • 财政年份:
      2018
    • 负责人:
      Smita Mohanty
    • 依托单位:
    REU Site: An REU Site in Interdisciplinary Chemistry at Oklahoma State University
    • 批准号:
      1559874
    • 项目类别:
      Standard Grant
    • 资助金额:
      $29.1万
    • 财政年份:
      2016
    • 负责人:
      Smita Mohanty
    • 依托单位:
    `Molecular Mechanisms of pheromone Perception: Role of Pheromone Binding Protein
    • 批准号:
      0628064
    • 项目类别:
      Continuing Grant
    • 资助金额:
      $62.42万
    • 财政年份:
      2006
    • 负责人:
      Smita Mohanty
    • 依托单位:
    Molecular Mechanisms of pheromone Perception: Role of Pheromone Binding Protein
    • 批准号:
      0414073
    • 项目类别:
      Continuing Grant
    • 资助金额:
      $50.4万
    • 财政年份:
      2004
    • 负责人:
      Smita Mohanty
    • 依托单位:
    海外基金