MRI: Acquisition of the First 800 MHz NMR Spectrometer with a Cryogenically Cooled Probe in the State of Oklahoma for Interdisciplinary Research and Training

在主要研究仪器（MRI）项目的支持下，俄克拉何马州立大学获得了一台800 MHz带冷冻探头的核磁共振仪器。该仪器将被安置在俄克拉荷马州全州共享核磁共振设施，以确保俄克拉荷马州和周边地区的研究人员可以使用它。新的光谱仪将支持下一代研究人员在现代最先进的核磁共振技术的培训。俄克拉何马州立大学通过课程和独立研究积极追求动手本科生研究培训。此外，化学系国家科学基金资助的“本科生科研体验”等项目面向全国招收本科生。少数民族本科生通过各种本科项目招募进行研究，如俄克拉何马州路易斯斯托克斯少数民族参与联盟（OK-LSAMP）。核磁共振（NMR）波谱是最强大的科学技术之一，可用于科学家阐明重要分子的结构。该仪器支持的项目涵盖化学生物学、蛋白质结构和功能、蛋白质动力学、RNA/DNA结构、复杂碳水化合物结构、新型聚合物设计和药物设计过程中的小复杂分子表征。新的核磁共振是研究人员在化学生物学，结构生物学，生物化学，分子生物学，微生物学和聚合物科学在俄克拉何马州和周边地区的重要资源。这些研究和教学努力的成果将通过学生和教师积极参加科学会议、专题讨论会和讲习班、同行评议出版物和将生物分子的原子坐标存入蛋白质数据库来传播。

With support from the Major Research Instrumentation (MRI) Program, an award has been made to Oklahoma State University for the acquisition of a 800 MHz NMR instrument with a cryoprobe. This instrument will be housed in the Oklahoma Statewide Shared NMR Facility to ensure that it is accessible to researchers in Oklahoma and the surrounding region. The new spectrometer will support the training of the next generation of researchers in modern state-of-the-art NMR techniques. Oklahoma State University is aggressively pursing hands-on undergraduate research training through courses, and independent research. In addition, programs in the Chemistry Department such as "Research Experience for Undergraduate Students (REU)" supported by National Science Foundation allows recruitment of undergraduate students across the country. Minority undergraduate students are recruited for research through various undergraduate programs such as the Oklahoma Louis Stokes Alliance for Minority Participation (OK-LSAMP). Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful scientific techniques that is available to scientist for the elucidation of the structure of important molecules. Projects supported by this new instrument span the range from Chemical Biology to protein structure and function, protein dynamics, RNA/DNA structure, complex carbohydrate structure, design of novel polymer, and small complex molecules characterization during the process of drug design. The new NMR is an essential resource for researchers in Chemical Biology, Structural Biology, Biochemistry, Molecular Biology, Microbiology, and Polymer Science across Oklahoma and the surrounding region. The results of these research and teaching efforts will be disseminated through active participation of students and faculty at scientific conferences, symposia and workshops, peer-reviewed publications and the deposition of atomic coordinates of biomolecules to the Protein Data Bank (PDB).