PIRE: Bio-Inspired Materials and Systems

Lashanda Korley，Jonathan Pokorski，Gary Wnek(凯斯西部储备大学)，Stuart Rowan(芝加哥大学)在自然中发现的材料显示出广泛的特性，包括对环境的响应，信号传输，以及适应支持生命的能力。向自然学习或仿生学可以成为设计、开发和获取下一代合成材料和系统的强大工具。此外，据估计，仿生概念将在全球经济发展中贡献1.2万亿美元，并已经为人们熟悉的尼龙搭扣和风力涡轮机等产品做出了贡献。因此，美国迫切需要培养下一代具有国际视野的仿生思想家，以开发新一波创新材料。因此，这个帝国汇聚了一个由美国和瑞士合作者组成的跨学科团队，在生物灵感材料和系统领域开展研究和教育。具体地说，帝国将利用来自自然的灵感来设计新的材料，这些材料可以随着环境的变化而改变韧性，更安全和更有效的生物植入，将传递神经样的电信号，并能够对环境做出反应以启动生物过程，所有这些都用于软机器人应用。一系列创新的教育和推广活动将培训美国学生学习自然和生物启发的哲学。这项培训将在国际范围内进行，瑞士合作者、世界仿生学概念和研究领域的领导者将参与其中。学生将接触到涉及化学、聚合物、物理、生物和工程学的主题，以开发多功能、活性材料。指导、多样性、文化能力、全球化和有效的科学交流被强调为PIRE的关键要素。大自然有许多复杂材料和系统的例子，远远超出了目前合成系统的能力。这一领域的创新潜力是巨大的，需要大规模的跨学科努力才能实现改变范式的科学突破。为此，凯斯西储大学(CWRU)、芝加哥大学(UOC)和瑞士弗里堡大学/阿道夫·默克尔研究所的仿生专家在生物启发材料和系统方面建立了国际伙伴关系。在聚合物合成、计算建模、机械表征、机器人、成像、制造、生物学、生物医学工程、物理和分子工程等领域合作优势的基础上，我们设想了五个生物启发材料和系统项目：(1)丝绸启发纳米复合材料：蜘蛛/卡迪蝇丝绸模拟物；(2)海参、鱿鱼喙和松果启发自适应复合材料；(3)可兴奋聚电解质纤维网络/凝胶：走向人造神经元；(4)由细胞外基质启发的动态和功能纤维；以及(5)由蠕虫运动启发的软机器人。这些研究的重点是开发用于软机器人系统的功能性、可编程和响应性材料。教职员工、研究生和本科生将在瑞士参与协同研究/教育活动。与当地仿生学思想领袖的教育和创新伙伴关系将指导下一代全球科学家和工程师在这一跨学科努力中的培训。通过与芝加哥科学与工业博物馆(MSI)的现有计划，将突出有效的科学传播。社区外展活动包括在CWRU和UOC为STEM中代表性不足的高中生提供研究机会，作为扩大的仿生使者计划的一部分，以及为每年参加马丁·路德·金的活动开发仿生动手演示。(MLK)克利夫兰自然历史博物馆的发现日。

LaShanda Korley, Jonathan Pokorski, Gary Wnek (Case Western Reserve University), Stuart Rowan (University of Chicago)Materials that are found in Nature display a wide range of properties including responsiveness to the environment, signal transmission, and the ability to adapt to support life. Learning from Nature or biomimicry can be a powerful tool in designing, developing and accessing the next generation of synthetic materials and systems. Furthermore, biomimetic concepts will account for an estimated $1.2 trillion in global economic development, and have already contributed to familiar products like Velcro and wind turbines. Thus, there is a critical need for the US to educate the next generation of internationally-minded biomimicry thinkers to develop a new wave of innovative materials. As such, this PIRE brings together an interdisciplinary team of US and Swiss collaborators to carry out research and education in the area of Bio-Inspired Materials & Systems. Specifically, the PIRE will utilize inspiration from Nature to design new materials that can change toughness in response to their environment, are safer and more effective biological implants, will transmit nerve-like electrical signals, and can respond to the environment to initiate biological processes, all for use in soft robotic applications. A range of innovative educational and outreach activities will train US students in learning from Nature and in a bio-inspired philosophy. This training will happen in an international context with Swiss collaborators, world leaders in biomimetic concepts and research. Students will gain exposure to themes cutting across chemistry, polymers, physics, biology, and engineering in the development of multi-functional, active materials. Mentoring, diversity, cultural competency, globalization, and effective scientific communication are emphasized as critical elements of the PIRE.Nature has a multitude of examples of complex materials and systems that go well beyond the current capabilities of synthetic systems. The innovation potential in this domain is vast and a large-scale interdisciplinary effort is required to realize paradigm-changing scientific breakthroughs. To that end, an international partnership between biomimicry experts at Case Western Reserve University (CWRU), the University of Chicago (UoC), and the University of Fribourg/Adolphe Merkle Institute in Switzerland in Bio-inspired Materials and Systems is established. Building upon collaborative strengths in polymer synthesis, computational modeling, mechanical characterization, robotics, imaging, manufacturing, biology, biomedical engineering, physics, and molecular engineering, five Bio-inspired Materials and Systems projects are envisioned: (1) Silk-inspired Nanocomposites: Spider/Caddisfly Silk Mimics; (2) Sea Cucumber, Squid Beak and Pine Cone Inspired Adaptive Composites; (3) Excitable Polyelectrolyte Fiber Networks/Gels: Toward Artificial Neurons; (4) Dynamic and Functional Fibers Inspired by the Extracellular Matrix; and (5) Soft Robotics Inspired by Worm Locomotion. These research thrusts are directed toward the development of functional, programmable, and responsive materials for deployment in soft robotic systems. Faculty, graduate, and undergraduate students will spend time in Switzerland engaging in synergistic research/educational activities. An educational and innovation partnership with local thought leaders in biomimicry will guide the training of the next-generation of global scientists and engineers in this interdisciplinary endeavor. Effective science communication will be highlighted via existing programming with the Museum of Science and Industry (MSI) of Chicago. Community outreach activities include research opportunities at CWRU and UoC for underrepresented high school students in STEM as part of an expanded Biomimetic Envoys program and the development of biomimetic hands-on demonstrations for annual participation in the Martin Luther King Jr. (MLK) Discovery Day at the Cleveland Museum of Natural History.