Integrating genetic, morphological, behavioral and demographic data to investigate primate life history

整合遗传、形态、行为和人口统计数据来研究灵长类动物的生活史

• 批准号: 1754024
• 负责人: James Higham
• 金额: $ 33.72万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-15 至 2023-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1754024&HistoricalAwards=false
• 关键词: Integrating; genetic; morphological; behavioral; demographic

Interpreting the human and primate fossil record is complicated by the fact that typically only skeletons and teeth are preserved. Yet many important aspects of primate and human biology are linked to variation in soft tissues, such as the degree of fat storage required for development and growth, or the degree of muscle development required for locomotion or within-species competition. In this project, the researchers will investigate the relationships among skeletons, soft-tissues, and reproduction across the lifespan, in the rhesus monkey population of Cayo Santiago, Puerto Rico. The project will advance knowledge about fundamental relationships among form, function, and behavior in non-human primates, which can inform our understanding of past primate and human biology. The project is an important part of research initiatives between New York University (NYU) and the Caribbean Primate Research Center, Puerto Rico, and builds on current initiatives to preserve and curate the Cayo Santiago skeletal collection as a valuable biological data resource. In addition, educational and public access programs will provide many opportunities for underrepresented minority students to participate in STEM research, both in the continental US and in Puerto Rico. The usual absence of soft-tissues from the fossil record presents a big challenge for assessing reproductive life histories from skeletal data in order to estimate the phenotypic variation on which natural selection acted, and to reconstruct the evolution of our species. This study will combine soft-tissue measurements of two entire social groups with detailed analyses of the entire Cayo Santiago adult skeletal collection, demographic, genetic parentage, and behavioral data, collected over more than six decades. The researchers will determine whether and to what extent variation in skeletal traits relates to fleshed measures of body size, body mass, body fat, and muscle size in two groups; determine the genetic and environmental sources of variation in both skeletal and soft tissue traits, and; determine the extent to which skeletal markers and soft tissue markers predict differences in fecundity and longevity in both females and males. The methods will combine morphometric measurement of both soft and hard tissues with quantitative genetic approaches.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

解释人类和灵长类动物的化石记录很复杂，因为它们通常只保存了骨骼和牙齿。然而，灵长类动物和人类生物学的许多重要方面都与软组织的变异有关，例如发育和生长所需的脂肪储存程度，或运动或物种内竞争所需的肌肉发育程度。在这个项目中，研究人员将在波多黎各圣地亚哥岛的恒河猴种群中调查骨骼、软组织和生殖之间的关系。该项目将促进对非人类灵长类动物形态、功能和行为之间基本关系的认识，这可以为我们了解过去的灵长类动物和人类生物学提供信息。该项目是纽约大学（NYU）和波多黎各加勒比灵长类动物研究中心（Caribbean Primate research Center）之间研究计划的重要组成部分，并建立在当前保护和管理圣地亚哥岛骨骼收藏作为宝贵生物数据资源的计划的基础上。此外，教育和公共访问计划将为未被充分代表的少数民族学生提供许多参与STEM研究的机会，无论是在美国大陆还是在波多黎各。化石记录中软组织的缺失给从骨骼数据中评估生殖生活史带来了巨大的挑战，从而估计自然选择作用下的表型变异，并重建我们物种的进化。这项研究将结合两个整个社会群体的软组织测量和对整个圣地亚哥岛成人骨骼收集的详细分析，人口统计，遗传亲子关系和行为数据，收集了60多年。研究人员将在两组中确定骨骼特征的变化是否以及在多大程度上与身体尺寸、体重、体脂和肌肉尺寸的实际测量有关；确定骨骼和软组织性状变异的遗传和环境来源；确定骨骼标记和软组织标记在多大程度上预测雌性和雄性在繁殖力和寿命方面的差异。该方法将软硬组织的形态测量与定量遗传方法相结合。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

The ontogeny of sexual dimorphism in free-ranging rhesus macaques.

• DOI: 10.1002/ajpa.24442
• 发表时间: 2022-03
• 期刊: AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY
• 作者: Turcotte, Cassandra M.;Mann, Eva H. J.;Stock, Michala K.;Villamil, Catalina, I;Montague, Michael J.;Dickinson, Edwin;Surratt, Samuel Bauman;Martinez, Melween;Williams, Scott A.;Anton, Susan C.;Higham, James P.
• 通讯作者: Higham, James P.